Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Tissue Mimicking Phantom"”.
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Real-time beam visualization and therapy planning for focused ultrasound therapies using a diagnostic imaging array
… therapeutic effects in localized regions of tissue through thermal elevations or mechanical stresses caused by an ultrasound wave. Although FUS therapy is effective at treating many different diseases, FUS therapy can be expensive and time-consuming because the treatment must be planned and …
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Deep structure ultrasound imaging using fundamental and third harmonic coded excitation techniques
… small anechoic targets (cysts) deep within a tissue-mimicking phantom. Golay coding with 1, 3 REC compounding was able to detect 3 mm and 2 mm diameter anechoic targets deep within the tissue-mimicking phantom while chirp 1, 3 compounding and conventional pulsing could only detect 4 mm …
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Engineering Considerations for Treatment of Prosthetic Joint Infections Using Alternating Magnetic Fields (AMF)
… temperatures of 65-80°C within 10-14 seconds. A tissue-mimicking phantom of the sheep leg was developed to evaluate heating with the system and to compare these results with numerical simulations. Single and intermittent AMF exposures of a tissue-mimicking phantom agreed with numerical …
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Creation of brain tissue-mimicking material and multi-material gradient 3D printer for magnetic resonance elastography phantom
… resonance elastography (MRE) is a non-invasive tissue imaging method that measures shear stiffness. While MRE has many benefits, it is not currently used clinically for scanning the human brain, mainly because it has not been validated with independent mechanical property testing methods. This …
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Temperature Mapping using Mid-Field Magnetic Resonance Imaging
… imaging modality with excellent soft tissue contrast and sensitivity to tissue temperature. MRI use is growing in Canada with expectation that this is expected to continue in the medium term, with more wide adoption of MRI and in particular a renewed focus on MR systems which deviate …
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Quantitative assessment of elasticity properties of skin using surface acoustic wave (SAW) method
Mechanical properties are important tissue parameters of skin that are useful for understanding skin patho-physiology, and aiding disease diagnosis and treatment. They are indicators of functional changes and pathological variations in the micro-structure. <br/><br/>This research thesis studies the …
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Ultrasonic Methods to Measure Shear Wave Velocity and Absorption for Tissue Viscoelasticity Characterization
Characterization of the viscoelasticity for soft tissues is useful for medical diagnosis. Various ultrasound and magnetic resonance-based techniques have been developed over the past few decades. With ultrasound methods, generating and tracing a shear wave (SW) propagating within the soft tissue …
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Tissue Oxygen Imaging for Non-invasive Metastasis Detection
… Simulations and bench top experiments in a tissue mimicking phantom were then used to determine PALI’s imaging depth. It was found that PALI has an imaging depth between 13 and 16 mm, which is deep enough to image most oral cavity metastases. To improve the imaging depth to image all oral …
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Design and Development of Multiscale Microscopic Imaging Systems for Neuroscience Applications
… imaging demonstrated negligible heating in tissue-mimicking phantom, highlighting the importance of similar excitation sources. The 2PM was converted into a further advanced three-photon microscope utilizing an excitation wavelength of 1300 nm. In a depth comparison study using brain …
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Passive monitoring of high-intensity focused ultrasound
… means of noninvasive ablation or hyperthermia of tissues such as tumors. Real-time monitoring of the progression of the field distribution of the HIFU transducer during treatment is important for localizing the intersection of the beam with the tissue. By continuously visualizing the HIFU field in …
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Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging
… resolved detector array technology in vitro, in tissue mimicking phantoms, in an ex vivo oesophageal model and in vivo in a mouse model. A hyperspectral linescan sensor was first integrated in a wide-field near-infrared reflectance based imaging set-up to assess the suitability of spectrally …
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Ultrasound-encoded optical tomography and time-reversed ultrasonically encoded optical focusing
… ultrasonic resolution to image soft biological tissue. We developed a photorefractive crystal-based, time-resolved detection scheme with the use of a millisecond long ultrasound burst to image both the optical and mechanical properties of biological tissues, with improved detection efficiency of …
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Applying synthetic aperture, coded excitation, and tissue harmonic imaging techniques to allow ultrasound imaging with a virtual source
… the axial resolution. The third technique was tissue harmonic imaging, which produces a narrower beamwidth and reduced sidelobes, and therefore can improve spatial resolution and contrast of images. Each technique is individually known to improve ultrasound image qualities, with its own …
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Investigation of Needle-Tissue Interaction during Ultrasonic Needle Intervention
… between the ultrasonic needle and soft tissue. Better and in-depth understanding of this interaction mechanism will help on both how to better design this ultrasonic needle device and how to achieve better operational performance and acquire real-time feedback information for medical …
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Non-invasive in vivo ultrasound temperature estimation
… The therapeutic temperature changes in target tissues range from few degrees for releasing chemotherapy drugs encapsulated in the thermosensitive liposomes to boiling temperatures in complete ablation of tumors via cell necrosis. High intensity focused ultrasound (HIFU) has emerged as a …
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Photoacoustic Reporter Gene Imaging And Optical Coherence Computed Tomography
… prominent merits. Because light interacts with tissue at the microscopic level through many distinct physical mechanisms, optical methods allow sensitive exploration of various aspects of the life down to the single-molecule level. From the technical perspective, optical systems utilize safe …
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Prostate Tissue Motion Tracking and Ultrasound Elastography Using Tissue Mechanics Derived Constraints
Current prostate cancer detection methods can be costly to obtain, such as magnetic resonance imaging, or lack specificity, such as a digital rectal exam. Ultrasound elastography, a method that can be used to develop and test algorithms that output stiffness, strain, and displacement data captured …