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Showing 1 to 20 of 122 for “"Time-of-flight mass spectrometry"”.
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Characterization of Molecular Glycerophospholipids by Quadrupole Time-of-Flight Mass Spectrometry
The physical properties of glycerophospholipids (GPLs) are not only determined by the head group (HG), but also by their fatty acid (FA) chains, which affect their distribution and function within membranes in the cell. Understanding the microheterogenity of lipid membranes on a molecular level …
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Surfactant Assisted Electrospray Ionization Time of Flight Mass Spectrometry of Synthetic Polymers
Synthetic polymers are complex mixtures which often require extensive characterization to determine chemical composition and structure. Mass spectrometric techniques have greatly enhanced the quantity, as well as the quality, of data that can be used to characterize synthetic polymers. Electrospray …
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Time-of-Flight Mass Spectrometry to Characterize Inorganic Coordination Complexes and Cyanobacteria
Matrix assisted laser desorption/ionization time-of flight mass spectrometry (MALDI-TOFMS) is used to study several inorganic coordination complexes and a variety of compounds from cyanobacteria. Also presented is a discussion of TOFMS instrumentation and the improvements in resolution and …
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Laser-Ionization Time-of-Flight Mass Spectrometry of High Molecular Mass Inorganic Complexes
Laser-Ionization Time-of-Flight Mass Spectrometry (LI-TOF-MS) is a sophisticated tool for the molecular-weight determination and structural characterization of a variety of molecules. Advances in instrumentation and ionization methods have recently expanded its role in the analysis of high-mass …
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Probing Base Metal Coordination Complexes Using Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry
… in the liquid phase but very little in terms of the gas phase. The purpose of this research is to further investigate these conditions and learn more about the reactions that can occur using Electrospray Ionization Quadrupole Time-of-Flight Mass Spectrometry (ESI QToF MS). This research …
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Analysis of Clinically Important Compounds Using Electrophoretic Separation Techniques Coupled to Time-of-Flight Mass Spectrometry
… (CE) separations were successfully coupled to time-of-flight mass spectrometric (TOFMS) detection for the analysis of three families of biological compounds that act as mediators and/or indicators of disease, namely, catecholamines (dopamine, epinephrine, norepinephrine) and their …
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Real time analysis of atmospheric single particles in urban environments using aerosol time of flight mass spectrometry
… determine the size-resolved chemical composition of single particles in real-time an ATOFMS was deployed at urban background sites in Paris and Barcelona during the MEGAPOLI and SAPUSS monitoring campaigns respectively. The particle types detected during MEGAPOLI included several carbonaceous …
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Characterisation of atmospheric single particles in industrial and regional background environments using aerosol time of flight mass spectrometry
The composition of atmospheric particles is an important factor in determining their impact on climate and health. In this study, an aerosol time-of-flight mass spectrometer (ATOFMS) was used to measure the chemical composition of ambient single particles at two contrasting locations – an …
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Measurement of soot precursor particles under atmospheric and low pressure conditions by means of time-of-flight mass spectrometry
… progress has been achieved in the understanding of the combustion of hydrocarbons. The gas phase reactions governing the first steps in the combustion process are well understood. The existing models describing the growth of soot particles and the formation of soot aggregates are widely accepted, …
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Development of methodology for the use of multi-bed sorbent traps with gas chromatography time of flight mass spectrometry
<p>The lipid peroxidation of unsaturated fatty acids in cellular membranes leads to the formation of alkanes, aldehydes, alkanals, alk-2-enals, and hydroxyl alkenals. The free radicals formed during the process of lipid peroxidation can react with and damage cellular components. Lipid peroxidation …
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DARK-PIGMENTED, AMOXICILLIN-RESISTANT, BACTERIAL SPECIES IN CHRONIC PERIODONTITIS MICROBIOTA IDENTIFIED WITH MATRIX ASSISTED LASER DESORPTION/IONIZATION TIME-OF-FLIGHT MASS SPECTROMETRY.
Dark-pigmented, gram-negative, anaerobic rods are often recovered in large numbers from the subgingival microbiome of human periodontitis, and are statistically associated with progression of chronic periodontitis. Due to their frequent expression of beta-lactamase enzymes, which hydrolyze and …
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Integrating Micro-Scale Separations to Matrix Assisted Laser Desorption and Ioniation Time of Flight Mass Spectrometry (MALDI-TOF-MS) for Protein Analysis
This dissertation describes the integration of micro-scale separations to matrix assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI TOF MS) for protein analysis. MALDI MS provides unsurpassed accurate mass measurements of intact bio-molecules, for example peptides and …
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The study of bimolecular radical reactions using a novel time-resolved photoionization time-of-flight mass spectrometry and laser absorption spectrometry apparatus
… a novel experimental apparatus that is capable of quantitatively measuring the concentrations of reacting gas-phase species and their reactive intermediates with sufficient time-resolution and sensitivity to determine both the kinetics and the product distributions of these systems. The …
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Probing the Low Temperature Oxidation of Furanic Biofuels, 2-Methyltetrahydrofuran and 2,5-Dimethylfuran, Utilizing Orthogonal Time-of-Flight Mass Spectrometry Coupled to Synchrotron Radiation
… global climate shifts has increased the focus of sourcing transportation fuels from depleting oil wells to regenerative, biological based solutions. One avenue of biologically sourced fuel involves the extraction of C5 and C6 sugars from the woody, fibrous, and inedible plant materials, …
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Characterizing organic colorants in mock-ups of a 15th-century Iranian Timurid Qur'an by direct analysis in real time time-of-flight mass spectrometry
<p>The Detroit Institute of Art (DIA) has in its possession a 15th century Iranian Timurid Qur’an (accession number 30.323) as the centerpiece of the Islamic Art Collection. The Qur’an manuscript pages are folio size, highly polished, and brightly colored. The pages are composed of 10 distinct …
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On-line screening of bioactive compounds and application of comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry for the analysis of birch bark
Rapid detection of bioactive compounds plays an important role in the phytochemical investigation of natural plant extracts.The hyphenated techniques, which couple on-line chromatographic separation and biochemical detection, are called high-resolution screening methods. In this system, …
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Proteomic comparison of Amoxicillin resistant and susceptible periodontal Provotella Intermedia and Provotella Nigrescens clinical isolation with Matrix-Assisted Laser Disportion Ionization Time-Of-/flight mass spectrometry
… pathogens in the etiology and progression of human chronic periodontitis. Because the bacterial species may not be adequately suppressed in the subgingival microbiota of chronic periodontitis lesions by conventional mechanical root debridement when present in high cultivable proportions, …
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Use of surface enhanced laser desorption/ionization-time of flight mass spectrometry (SELDI-TOF MS) to study protein expression in a rat model of cocaine withdrawal
SELDI-TOF MS is an analytical technology that combines chromatography and mass spectrometry. It is being exploited for the measurement of numerous proteins in serum, less often in organ tissue (rarely in brain). We applied SELDI-TOF MS technology to study protein expression in the brain of rats …
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