Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Time-of-flight SIMS"”.
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Applying secondary ion mass spectrometry to cellular and model membranes to image component distribution and quantify composition
Abstract Secondary ion mass spectrometry (SIMS) returns chemically specific data on membrane component distribution and composition. Of particular interest is a membrane protein’s lipid environment, which may play a role in the protein’s function. Herein, this thesis describes the synthesis of …
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Secondary ion mass spectrometry as a tool to evaluate chemical composition within model and cellular membranes
… tools to elucidate the chemical distribution of lipid components within the eukaryotic cellular membrane is critical to understanding their role in many cell processes. Secondary ion mass spectrometry (SIMS) is a technique that offers both chemical and spatial specificity, and has become …
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Using imaging secondary ion mass spectrometry to determine mammalian plasma membrane component distribution and cell differentiation state
The organization of the plasma membranes of mammalian cells has been studied for over forty years, with our understanding evolving from the fluid mosaic model of Singer and Nicholson to a more nuanced model acknowledging lateral heterogeneity in protein and lipid distributions. Within this area of …