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Showing 1 to 2 of 2 for “"Tim3 pathway"”.
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Differential gene expression in Behcet's disease and differential anti-tumor effects of Tim3 pathway blocking molecules
… anti-tumor effects of three forms of Tim-3 pathway blocking molecules Tim-3 is a molecule containing T cell immunoglobulin variable region (IgV)-like domain and mucin-domain, and known to suppress Th-1 immune response. In a previous study, blocking Tim3 pathway increases anti-tumor immunity …
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The Suppressive Mechanisms of TIM3 on T Cell Cytokine Production and The Anti-Tumor Effect of TIM3-Pathway Inhibition
… and mucin-domain-containing molecule-3 (TIM3) has been shown to be expressed on Th1 cells and negatively regulates these cell functions. TIM3 has been implicated in the Th1-driven pathogenesis of autoimmune disease and the viral infection. However, molecular mechanisms of TIM3 inhibiting …