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Showing 1 to 20 of 115 for “"Thyroid hormone"”.
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Synthesis of novel thyroid hormone analogues
… on the ring may lead to even more potent anti-thyroid drugs.
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Extrathyroidal thyroid hormone activation in ring doves
… observed period of greatest increase in plasma thyroid hormone concentrations during the first 6-8 days posthatch in ring doves. These results are the first demonstration of initial velocity 5’D activity during development in an altricial bird species and demonstrate a correlation between …
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Regulation of Secretory Phospholipase A2 by Thyroid Hormone
… atherosclerosis. The potential linkage of hypothyroidism with inflammation led us to examine the modulation of sPLA2 expression by thyroid hormone (T3) in liver.</p> <p>Objective: Most of the studies of phospholipase A2 group IIA (PLA2g2a) have been conducted with macrophages and vascular …
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The Alteration of Thyroid Hormone Level during Liver Transplantation
… free-triiodothyronine(FT3), free-tyroxine(FT4) thyroid stimulating hormone(TSH) 농도를 측정하였다. Cytokines들 중 IL-6의 값도 같은 시점에 측정하였다. 결과: 측정한 갑상선 호르몬 중 혈중 T3, T4, TSH 농도는 마취유도후 시행한 결과보다 무간기, 수술 끝나기 30분전, 수술 24시간 후, 수술 120시간 후에 유의하게 감소하였다. 특히 혈중 T3 농도는 무간기에 시행한 결과에 비해서도 수술 24시간 후, 수술 120시간 후에 유의하게 …
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Cyborg Butterflies, Liminal Medicine: Thyroid Hormone Treatment, 1890-1970
In this thesis, I develop a history of thyroid hormone treatment (THT) that centers on the bodies of animals and women between 1890 and 1970. This history contextualizes the current debate between two forms of THT, desiccated and synthetic. Drawing on the discourses present in biomedical journals, …
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Thyroid hormone action and disruption in the brain: Xenopus as a model to study disruption of thyroid hormone availability on early brain development
Thyroid hormones (TH) are essential for normal brain development in vertebrates. Disruption of TH action, either due to genetic and/or environmental factors, has been implicated in neurological defects such as autism, attention deficit hyperactivity disorders (ADHD) and IQ loss. On average, over 30 …
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Retinoic Acid Regulation of Thyroid Hormone Action in Bone Cells
<p>Retinoic acid and thyroid hormone are known to play key roles in the regulation of endochondral ossification. However, the issue of whether these two hormones interact with each other to regulate bone functions remains to be established. We investigated how thyroid hormone and retinoic acid …
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NICOTINE MODULATION OF THYROID HORMONE SIGNALING AND ITS CONTRIBUTION TO COGNITION
… including disruptions to endocrine function. Thyroid hormones may specifically be affected by nicotine exposure through cigarette smoke. The present work begins with a thorough analysis of the literature on thyroid hormones, their contribution to cognition and synaptic plasticity as well as …
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Thyroid Hormone Effects on Sertoli Cell Gene Expression in the Rat
Thyroid hormones, along with other hormones such as follicle stimulating hormone (FSH), regulate neonatal Sertoli cell development. It was not clear however, if all of the changes seen in Sertoli cell development during hypothyroidism represent direct effects of thyroid hormone deficiency on the …
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Actions of thyroid hormone on myocardial contractility in the intact animal
The central role of the mammalian heart in the circulation was recognised by Nei Chung when he wrote in his Third Book of the Yellow Emperor's Classic of Internal Medicine (2698 - 2598 B.C.): Treatise on the Five Viscera in Relation their part in Perfecting Life, "The Heart is in accord with the …
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Molecular mechanisms of thyroid hormone transport: the role of amino acid transporters
Thyroid hormones (TH) exert their multitude of effects on body development,<br/>growth and metabolism largely via transcriptional regulatory pathways. TH-induced transcription is controlled by receptors present in the cell nucleus,<br/>therefore extracellular TH must first cross the plasma membrane …
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Effects of Thyroid hormone on Cardiomyocytes and on Glioma differentiation and proliferation
The action of thyroid hormone (TH) on cell growth, differentiation and survival during development may be of therapeutic relevance. The present study investigated the potential effects of long-term TH treatment on cardiomyocytes and on glioma tumour cell lines. This study employed neonatal …
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Salsalate Inhibition of Thyroid Hormone Transport : A Model of the Euthyroid Sick Syndrome
<p>Multiple alterations of serum thyroid hormone metabolism have been noted in essentially all severe systemic nonthyroidal illnesses (Nil). This spectrum of abnormalities is collectively termed the “euthyroid sick syndrome”. One putative mechanism is the presence of circulating thyroid hormone …
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The Influence of The Thyroid Hormone on Body Water Compartments in The Dog
Made available in DSpace on 2014-12-05T22:14:39Z (GMT). No. of bitstreams: 1 5900547.pdf: 4561615 bytes, checksum: 0bfb3980d06d510b9ab7af233af2902f (MD5) Previous issue date: 1958
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Thyroid hormone activation by intestinal tissue of high and low weight-selected chickens
… decreased abruptly at 1d posthatch. Both plasma hormones were higher at each perinatal stage in the LW line than in the HW line and the LW line hatched earlier than HW. Intestinal alkaline phosphatase (a marker of differentiation) showed a significant increase in activity at each of the stages of …
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Decreased Triiodothyronine Binding to the Hepatic Nuclear Thyroid Hormone Receptor in the Diabetic Mouse
… C57BL/KsJ-<em>db m</em> mouse has abnormal thyroid hormone levels and indications of thyroid hormone resistance. To investigate the basis of these abnormalities, the hepatic nuclear thyroid hormone receptor was extracted with 0.4 M KCl, 1.1 mM MgCl<sub>2</sub>, 20 mM Tris/HCl, pH 7.9 from …
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Effect of the ligands of thyroid hormone receptor on non-alcoholic fatty liver disease
… disease. Here, we examined the effect of the thyroid hormone triiodothyronine (T3) and the agonist of the thyroid hormone receptor β isoform (TRβ), GC-1, on fatty liver and steatohepatitis induced in rodents by a choline-deficient, methionine-restricted (CMD) diet. Male Fischer rats fed the …
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Alterations in Vitamin a and Thyroid Hormone Metabolism in Anorexia Nervosa and Associated Disorders
Vitamin A and thyroid hormone metabolism was investigated in subjects with anorexia nervosa. Subjects referred to the Eating Disorders Clinic were selected for the study if they had experienced a weight loss of (GREATERTHEQ) 15% of original body weight and had a basal metabolic rate (BMR) of …
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Approaches for assessing the presence and impact of thyroid hormone disrupting chemicals in delphinid cetaceans
… (OH-PCBs). OH-PCBs may then interfere with thyroid hormone dependent neurodevelopment. The goals of these studies were to investigate the relationships between lipid dynamics and PCB effects and to devise a quantitative approach to assess neurodevelopment in delphinid cetaceans. Blubber …
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