Global ETD Search

AGE-RELATED GUT DYSBIOSIS ACCELERATES THYMIC INVOLUTION AND ALTERS PERIPHERAL T CELL REPERTOIRE IN DUCHENNE MUSCULAR DYSTROPHY

TRIPODI, LUANAUniversità degli Studi di Milano2024

Emerging researches highlight a significant interplay between the immune system and skeletal muscle, particularly in the context of inflammatory muscle disorders and dystrophic conditions like Duchenne Muscular Dystrophy (DMD), as well as during the natural process of muscle regeneration. …

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Study of the androgenic activity of the regenerating adrenal cortex.

Forester, George V.University of Ottawa (Canada)2009

… increase in glucocorticoid activity, assessed by thymic involution. Similar treatment to enucleated animals caused a transient increase in the androgen level but failed to cause thymic involution. ACTH treated warm exposed castrated and dual operated animals displayed a small non-significant …

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Characterization of Non-Coding RNAs in Regulating Thymic Epithelial Cell Responses to Pathophysiological Stress

Hoover, Ashley Renae2018

… forms of stress. Stress initiates a transient involution that can reduce overall thymic volume up to 90%. The thymus is predominantly composed of developing thymocytes and specialized epithelial cells. The type of stress predicates whether the thymocytes or epithelial cells initiate the …

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Characterization of Stress Responsive MicroRNAs and Their Roles in T Cell Development

Belkaya, Serkan2014

… diverse mRNAs. We hypothesized that a subset of thymically encoded miRs would be stress responsive and modulate thymopoiesis. Thymic miR profiling revealed 18 distinct miRs that are dysregulated more than 1.5-fold in response to lipopolysaccharide or the synthetic glucocorticoid dexamethasone. …

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The effects of treadmill and voluntary wheel training on morbidity and inflammation during ulcerative colitis in mice

Cook, MarcUniversity of Illinois at Urbana-Champaign2013

… that FTR resulted in adrenal hypertrophy and thymic involution indicate that, while this training model has demonstrated many physiological benefits, it may be a chronic stressor. In contrast, we observed that VWR significantly reduced morbidity and colonic inflammation in DSS treated mice. …

uiuc Repository record for The effects of treadmill and voluntary wheel training on morbidity and inflammation during ulcerative colitis in mice (opens in a new tab)

CXCR3high CD8+ T cells with naive phenotype and high capacity for IFN-γproduction are generated during homeostatic T-cell proliferation

Ogura(Kato), AikoKyoto University2019

kyoto Repository record for CXCR3high CD8+ T cells with naive phenotype and high capacity for IFN-γproduction are generated during homeostatic T-cell proliferation (opens in a new tab)