Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Thrombophilia"”.
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Detection of Genetic Thrombophilia (Fa V Leiden & PT20210 mutation) using GeneXpert Technology with IQCP Implementation
<p>Abstract</p> <p>Individuals having Genetic Thrombophilia pose a higher risk of having a thrombotic event. It is crucial to determine these gene variants to prevent a possible episode of thromboembolism. With the current PCR method, it involves individual processing of DNA isolation, …
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Prevalence of known thrombophilia and incidence of venous thromboembolism in pregnant woment in the Western Cape Province of South Africa
Venous thromboembolism (VTE) is a major cause of maternal mortality worldwide. In many developed countries, all maternal deaths are investigated, and accurate statistics are available. In United Kingdom (UK) for example, VTE is the leading cause- and is increasing despite heightened awareness of …
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Evaluation of Current Thrombophilia Screening Practices of Internists, Family Physicians, and Obstetricians/Gynecologists: Factor V Leiden Genetic Testing and Referral Patterns
<p>Thrombophilia is a complex, multifactorial condition in which the patient exhibits an increased susceptibility to form blood clots, especially in the veins of the lower extremities. A mutation in the gene encoding for factor V, known as factor V Leiden (FVL), is the most common cause of …
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Thrombophilie als mögliche Ursache für vorzeitige Plazentalösung
… correlation between placental abruption and thrombophilia. 56 women of Caucasian origin in the age-bracket of 20 to 41 years participated in the study. The 56 women were treated in the gynaecological department of the RWTH Aachen between 1994 and 2001 because of premature placental abruption. …
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"A syndrome so characteristic" Molecular and clinical studies of Fusobacterium necrophorum and Lemierre's syndrome
… Lemierre’s syndrome were screened for underlying thrombophilia and concomitant Epstein-Barr virus (EBV) infection and the clinical spectrum was described. On admittance, patients with Lemierre’s syndrome were severely ill, in a majority fulfilling the criteria for severe sepsis. Underlying …
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Living with a long-term condition: a grounded theory.
… potentially life-threatening, health condition. Thrombophilia offers an example of a little-researched condition which may not affect people significantly on a day-to-day basis, but can lead to acute illness. The second condition under consideration, asthma, was selected due to its similarity in …
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VENOUS THROMBOEMBOLISM IN SOUTHERN SWEDEN EPIDEMIOLOGY AND RISK FACTORS
… risk factors for VTE. Concomitant malignancy and thrombophilia were especially common in UEDVT, and mortality was high among UEDVT patients with malignancy at diagnosis. Female VTE patients < 50 years of age with the FVL-mutation had higher median Hb compared to female patients without the …
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Thrombosis in Children
… significantly increased prevalence of inherited thrombophilia. Also, autoantibodies against prothrombin were significantly more often detected than in controls, suggesting immunological pathogenesis. Pediatric thrombosis often seem to be elicited by a combination of risk factors. Girls receiving …
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Cloning and targeted deletion of the mouse histidine rich glycoprotein gene and functional characterization of HRG in mice
… glycoprotein deficiency with familial thrombophilia have been reported. Therefore, we analyzed mainly effects of HRG on blood coagulation and fibrinolysis. Antithrombin activity in plasma of Hrg-/- mice was higher than in plasma of heterozygous Hrg+/- or wild-type Hrg+/+ mice in the …
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Stroke ischemico arterioso perinatale: valutazione clinica e dei fattori di rischio associati
Con un'incidenza che varia da 1/2800 a 1/5000 nati vivi, lo stroke ischemico arterioso perinatale è la più frequente forma di infarto cerebrale in età pediatrica. Il 40% dei pazienti non presentano sintomi specifici nel periodo neonatale e la diagnosi viene posta tardivamente per l'insorgenza di …
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Erstellung und Erprobung eines wissensbasierten Systems zur Unterstützung der Labordiagnostik der Thrombophilie
Bei der vorliegenden Arbeit wurde ein wissensbasiertes System für die Erstellung von Befundvorschlägen in der Thrombophilie-Diagnostik mit Hilfe der Notation Pro.M.D. erstellt.<br><br>Besonders bei der Gerinnungsdiagnostik ist es erforderlich, zielgerichtet und rationell weiterführende …
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Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies.
Abstract The last two decades has seen an avalanche of studies establishing Activated protein C (APC) resistance due to Factor V Leiden mutation as the most prevalent genetic risk factor, yet known, for venous thromboembolism. This has been documented in 20-60% of patients with deep vein thrombosis …