Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"Thromboembolism"”.
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VENOUS THROMBOEMBOLISM IN SOUTHERN SWEDEN EPIDEMIOLOGY AND RISK FACTORS
Despite the fact that venous thromboembolism (VTE) is an important cause of morbidity and mortality there is still insufficient information on VTE risk factors and patient characteristics in the general population. Previously published incidences of VTE (deep venous thrombosis [DVT] and pulmonary …
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¿ROLE OF ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF UNPROVOKED VENOUS THROMBOEMBOLISM¿
Background and Aim Venous thromboembolism (VTE) is a multifactorial disease that includes deep vein thrombosis (DVT) and pulmonary embolism (PE). VTE patients can be classified on the basis of the risk factor(s) that trigger the thromboembolic event. Indeed, up to 50% of VTE events occur in absence …
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Inpatient & Outpatient Venous Thromboembolism: A Multifactorial Approach to Increase Mechanical and Pharmacological Prophylaxis Compliance
<p>Venous thromboemboli (VTEs) are a clinical and public health problem as they are commonly linked to inpatient experiences, yet frequently occur in the outpatient setting. VTEs place a significant burden on health care organizations and patients alike, as VTEs are costly, require long-term …
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Real-world Pharmacological Anticoagulation and Clinical Outcomes of Venous Thromboembolism in Adults with Sickle Cell Disease
… considered as a hypercoagulable state and venous thromboembolism (VTE) is a serious disease-specific complication. However, there have been limited real-world studies on VTE in SCD patients. This work aims to provide a comprehensive assessment of the risk factors and treatment of VTE in adults …
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Risk assessment and mortality prediction in patients with venous thromboembolism using big data and machine learning.
Venous thromboembolism (VTE) is the third most common cardiovascular condition that affects mainly hospitalized and cancer patients and it is associated with high morbidity and mortality. Some patients need immediate treatment and monitoring in intensive care units (ICU). Moreover, cancer patients …
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Retrospective review of the incidence of venous thromboembolism in pregnancy and the puerperium and identification of presenting complaints of pregnancy-related venous thromboembolism at Groote Schuur Maternity Centre, Cape Town between 1 January 2016 and 31 December 2016
Background: Venous thromboembolism is one of the leading causes of morbidity and mortality around the world. In addition to the immediate morbidity, there is significant implications on delivery plans, future options of contraception and thromboprophylaxis in subsequent pregnancies. At present, no …
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A Comprehensive Profiling of Hemostatic Activation and Thromboinflammatory Biomarkers and Cellular Indices in Predicting Outcomes in Venous Thromboembolism
Despite advancements in diagnostic and therapeutic approaches, pulmonary embolism (PE) and deep vein thrombosis (DVT) in general remain challenging conditions due to their complex pathophysiological mechanisms. This thesis aims to comprehensively profile and evaluate the prognostic value of blood …
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Prevalence of known thrombophilia and incidence of venous thromboembolism in pregnant woment in the Western Cape Province of South Africa
Venous thromboembolism (VTE) is a major cause of maternal mortality worldwide. In many developed countries, all maternal deaths are investigated, and accurate statistics are available. In United Kingdom (UK) for example, VTE is the leading cause- and is increasing despite heightened awareness of …
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The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism
Purpose: There are conflicting results from studies on whether the ventilation (V) scintigraphy can be safely omitted or replaced by a chest x-ray. These studies were based on planar ventilation perfusion (V/Q) scintigraphy. We evaluated the value of the V single photon emission computed tomography …
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Vascular biology in the menstrual cycle, pregnancy and pre-eclampsia
… in women of reproductive age. Thrombosis and thromboembolism are the most common causes of maternal death in the United Kingdom. Pre-eclampsia is associated with increase in immediate and lifetime risk of adverse thrombotic events. Both pregnancy and the follicular phase are associated with …
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Comparison of echocardiography and computed tomography for characterization of cardiac clots in cats with heart disease
Arterial thromboembolism (ATE) is a devastating and life-threatening condition in cats most commonly secondary to heart disease. Echocardiography is the reference standard to evaluate for presence of a clot or its precursor known as spontaneous echocardiographic contrast (SEC or “smoke”) within the …
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Sickle cell disease
… splenic infarction related to altitude, venous thromboembolism and sudden death in athletes.
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Cardiovascular Disease: Prevention and Management
… decrease risk of venous vascular events (venous thromboembolism) in women taking hormone therapy (HT).1–3 However, these drugs have little effect on heart failure outcomes, an important source of morbidity and mortality in the United States. This dissertation will have two projects concerning …
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Development, testing, and evaluation of the central-flow, double- leaflet heart valve
… pressure drop, turbulence, hemolysis, and thromboembolism could be a significant contribution. A central-flow, double-leaflet valve was developed. The wear, pressure drop, turbulence, and regurgitation associated with the new valve were evaluated. The wear test results indicated the need …
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The Development of a Computational Model of Thrombosis in Hemodialysis Catheters
Thromboembolism (TE) significantly limits the usefulness and safety of blood-contacting devices such as hemodialysis catheters. Computer simulation of TE can provide understanding of the process and can facilitate the design of more effective devices. Previous work conducted at BYU successfully …
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Detection of Genetic Thrombophilia (Fa V Leiden & PT20210 mutation) using GeneXpert Technology with IQCP Implementation
… gene variants to prevent a possible episode of thromboembolism. With the current PCR method, it involves individual processing of DNA isolation, amplification, and detection using three (3) different instruments resulting to an increased turnaround time of 5 to 7 days and additional staff …
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Platelet Receptor Glycoprotein VI in Ischaemic Stroke
… activation, thrombus growth and subsequent thromboembolism underpins the pathophysiology of ischaemic stroke. At sites of atherothrombotic plaque rupture, it is established that platelet surface receptor glycoprotein (GP) VI-dimer binds to exposed sub-endothelial collagen, initiating the …
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ADAMTS13 Activity in Dogs with Chronic Enteropathies
… those with protein losing enteropathy and thromboembolism.
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A Comparative In Vitro Study of the Flow Characteristics Distal to Mechanical and Natural Mitral Valves
… to blood constituents, which could lead to thromboembolism. In the ongoing effort to reduce long-term complications and morbidity, it is imperative that we better understand the flow characteristics of the natural valve as well as that of the mechanical valve. In this study, we overcome many …
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NOVEL REGULATORS OF GPVI-MEDIATED PLATELET ACTIVATION
… WT littermate controls. In an in vivo pulmonary thromboembolism model, ELMO1-/- mice showed reduced survival compared to WT littermate control. ELMO1-/- mice also showed shorter time to occlusion using the ferric-chloride injury model and reduced tail bleeding times compared to WT littermate …
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