Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Thrombocytosis"”.
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Evaluating the Diagnostic Value and Molecular Mechanisms of Thrombocytosis in Lung Cancer
… thesis investigates the role of thrombocytosis as an indicator of lung cancer in primary care, integrating electronic health record analysis with mechanistic in vitro investigations to evaluate its diagnostic value and underlying biology. The first and largest phase, evaluates the …
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The Role of Platelets In Ovarian Carcinoma
… factors in the human body. The observation that thrombocytosis (platelet count >450,000/uL) occurs in patients with solid malignancies was made over 100 years ago. However, the clinical and biological implications as well as the underlying mechanism of paraneoplastic thrombocytosis associated …
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Implementation of the JAK2V617F mutation analysis in the pathway of suspected myeloproliferative neoplasms in Groote Schuur Hospital
… erythrocytosis, OR leukocytosis and/or thrombocytosis and/or splenomegaly; OR patients with thrombosis without cytoses. Patients were investigated for MPN and managed in the haematology clinic of Groote Schuur Hospital. We studied the association of clinical and laboratory variables with …
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Platelets and Anti-Angiogenic Resistance In Ovarian Carcinoma
… significant reservoir of angiogenic regulators. Thrombocytosis has been shown to be caused by malignancy and associated with adverse clinical outcomes, however the causal connections between these associations remain to be identified.</p> <p>Materials and Methods: Following IRB approval, patient …
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Determinants of clinical phenotype in myeloproliferative neoplasms
… in polycythemia vera. Patients with essential thrombocytosis however, were found to have high levels of GROalpha and EGF, and levels of these at single time points or when measured longitudinally were predictive for the risk of progression to myelofibrosis. Conclusions: Comprehensive genomic …
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Pulmonary tuberculosis in the elderly : diagnostic criteria and its epidemiology in old age homes
… normocytic anaemia (70%), leucocytosis (55%), thrombocytosis (33%), rapid ESR in 90%, lymphopenia (22%) and monocytopenia (37%); hyponatraemia (60%), hypokalaemia (42%) and hypoalbuminaemia (83%), serum bilirubin (20%) and alkaline phosphatase, aspartic transaminase and lactic dehydrogenase are …