Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Thioredoxin system"”.
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Characterization of the thioredoxin system in Methanosarcina mazei
Thioredoxin (Trx) and thioredoxin reductase (TrxR) along with an electron donor form a thioredoxin system. Such systems are widely distributed among the organisms belonging to the three domains of life. It is one of the major disulfide reducing systems, which provides electrons to several enzymes, …
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Thioredoxin-mediated reduction of photosynthetic carbon reduction enzymes following chilling in the light
… from both plants was effectively reduced by thioredoxin. The chilling treatment had no effect on the midpoint potential of the regulatory sulfhydryl groups ($-$310 mV), indicating no direct chilling damage to the enzyme. Thiol labeling of FBPase in vivo showed that there was a 60% decrease in …
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Disruption of mitochondrial redox homeostasis as a cellular signal.
… of ROS, mitochondria contain protein antioxidant systems to help maintain thiol homeostasis. Mitochondria are emerging as an important redox signalling node and are involved in a myriad of signalling pathways, which have a redox component, either through a response to a particular ROS or the shift …
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Computer modelling applied to the Calvin Cycle
… their use in the investigation of biochemical systems, principally the photosynthetic Calvin cycle. A set of metabolic modelling software tools, "Scampi", constructed as part of this project is presented. A unique feature of Scampi is that it allows the user to make a particular model the …
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Metabolic Manipulation of Glutathione as an Anticancer Therapeutic Target
… suggests combined inhibition of glutathione and thioredoxin, another intracellular antioxidant, is required for anticancer effects in established tumours. Auranofin is a putative inhibitor of the thioredoxin system. HCT 116 p53-/- cells were resistant to auranofin at doses that HCT 116 p53+/+ …
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Analyse der physiologischen Funktion von Mitgliedern der Rieske-Typ Eisen-Schwefel-Proteinfamilie in der inneren Plastidenhülle
… wurden Tic55, PTC52 und PAO als Thioredoxin (Trx)-Targets in der inneren Plastidenhülle identifiziert. Abgesehen von konservierten Rieske- und [2Fe-2S]-Clustern weisen diese Proteine ein CxxC-Motiv auf. Aktivitätsmessungen in An- bzw. Abwesenheit von stromalem Trx f bzw. Trx m …
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Σχεδιασμός, σύνθεση και αξιολόγηση πεπτιδικών και μη πεπτιδικών αναλόγων της εκλυτικής ορμόνης των γοναδοτροπινών (Gonadotropin Releasing Hormone, GnRH)
Η εκλυτική ορμόνη των γοναδοτροπινών (GnRH ή LHRH) είναι ένα δεκαπεπτίδιο υπεύθυνο για τον έλεγχο και την απελευθέρωση των γοναδοτροπινών ορμονών LH και FSH και κατ’ επέκταση για τη ρύθμιση της λειτουργίας του αναπαραγωγικού άξονα. Τροποποιημένα πεπτιδικά ανάλογα της GnRH χρησιμοποιούνται για τη …