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Showing 1 to 3 of 3 for “"Thioredoxin reductase-1"”.
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자궁내막증 자궁내막에서의 세포증식 증가와 thioredoxin reductase-1 발현의 증가
… 자궁내막증을 가진 여성의 자궁내막 용종의 발생율 및 세포의 증식도, Bcl-2 단백질과 thioredoxin reductase-1 (TrxR-1)의 발현 정도를 알아보고자 하였다. 연구대상 및 방법 : 복강경과 자궁경을 시행받은 총 631명의 불임 여성 중 자궁내막증을 가진 434명을 실험군으로 자궁내막증이 없는 197명을 대조군으로 하여 자궁내막 용종의 발생율을 조사하였다. 이후 양군에서 얻은 자궁내막조직으로 Ki-67, Bcl-2 단백질과 TrxR-1의 발현을 알아보기 위해 면역조직화학염색법으로 염색한 후 컴퓨터 프로그램 …
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Targeting The Redox System to Overcome Mechanisms of Drug Resistance In Chronic Lymphocytic Leukemia
… co-culture protection. Increased expression of Thioredoxin Reductase 1 (TxnR1), the target of Auranofin was seen in CLL cells upon stromal co-culture. High apoptotic induction in CLL and minimal cytotoxicity towards stromal cells warrant further examination of Auranofin for CLL therapy. The …
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Differential proteome analysis of human lung epithelial cells following exposure to aromatic volatile organic compounds
… observed at both the reactive centers of thioredoxin reductase 1, which is a key element in the control of the cellular redox state, may be involved in styrene-induced ROS formation and apoptosis. A similar proteomic approach has been carried out with the halobenzenes CB and 1,2-DCB …