Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 157 for “"Thiols"”.
-
Distribution of thiols in the northwest Atlantic Ocean
… and glutathione, two low-molecular weight thiols, from the coastal northwest Atlantic Ocean and the Bermuda Atlantic Time Series (BATS) sampling site in the Sargasso Sea, a first for these regions. These two thiols were found in the upper 200 meters of the ocean at all sites, and the total …
-
Distribution of thiols in the northwest Atlantic Ocean
… and glutathione, two low-molecular weight thiols, from the coastal northwest Atlantic Ocean and the Bermuda Atlantic Time Series (BATS) sampling site in the Sargasso Sea, a first for these regions. These two thiols were found in the upper 200 meters of the ocean at all sites, and the total …
-
Development of novel techniques for monitoring anti-oxidant thiols
The clinical exploitation of physiological biomarkers could yield considerableimprovements in diagnosis and treatment providing their measurement can be conducted peedily and preferably at the point of care. The project has sought to investigate the development of new methods that could allow such …
-
Development of a synthetic enzyme for detection and quantitation of Thiols
A voltammetric survey of quinone and ferricinium derivatives showed that several are useful for electrocatalytic thiol oxidation. Those showing the highest rates are the quinone form of dihydroxybenzylamine and the dimethylaminomethylferricinium ion, which oxidize glutathione at rates of 18 $\rm …
-
Stereoselective synthesis of 1,2-disubstitued βeta-amino alcohols and amino thiols
This thesis covers the development and implementation of two distinct methodologies, both of which provide access to enantiomerically enriched, vicinally functionalized products. Chapter 1 provides background and a brief introduction of the activation of Group 16 Lewis acids by Lewis bases. Chapter …
-
Modulation of thiols and pulmonary immune responses due to diesel exhaust particle (DEP) exposure
Environmental exposure to diesel exhaust particles (DEP) has been of concern because of its potential contribution to the increased prevalence of acute and chronic airway diseases. The objective of this study was to investigate the role of thiol changes (due to DEP exposure) in immune responses. …
-
A Study of the Mechanism of Phenol and Amine thiols as Antifatigue Agents by ESR
The reaction of 4-mercaptoacetami dodiphenylamine (MADA) with natural rubber latex in the presence of a free radical redox system consisting of tert-butyl hydroperoxide /tetraethylenepentamine has been investigated. A colormetric method has been used to estimate the concentration of the bound MADA. …
-
The role of thiols in nitric oxide donor chemistry: Studies using product analysis and a novel proteomics technique.
The role of thiols in nitric oxide donor chemistry: Studies using product analysis and a novel proteomics technique.
-
I. Efforts Toward the Total Synthesis of (-)-Crambidine. II. Reactions of Azy(3-Me)-Containing Peptides With Thiols and Selenols
… peptides has been performed. While thiols were found to have low reactivity with this class of electrophilic peptide residues, two S-linked glycopeptides were successfully synthesized. Benzeneselenol was found to be highly reactive with Azy(3-Me)-containing peptides, and a variety of …
-
Synthesis and transformations of 2-thiocarbohydrates
… 2-thiocyanates were reduced to the corresponding thiols using appropriate reagents and reaction conditions. The screening of substrates, stereochemical outcome and the reaction mechanism are discussed briefly (Scheme I). Scheme I. Synthesis of the 2-thiocyanates II and reductions to 2-thiols III & …
-
Tailored Materials for Surface-Enhanced Raman Spectroscopy
… by altering the adsorbed thiol. Mixtures of thiols have been used to provide a wider range of surface properties but there is considerable uncertainty surrounding the mechanism of thiol adsorption, and so the aim of this project has been to develop an understanding of the kinetics and …
-
Drivers of Sauvignon blanc aroma at harvest: C6 compounds, antioxidants, and sulfur
… mainly focused on the release of varietal thiols from conjugated precursors. An alternative pathway was shown to have immense potential to form 3-mercaptohexanol (3MH) via the addition of H2S to C6 compounds. However, both pathways have limitations to their relevance in oenological …
-
Diallyl polysulfides from garlic: mode of action and applications in agriculture.
… low molecular weight (LMW) and protein thiols. In this study the interaction between DAS and LMW thiols was investigated and for the first time the reduced DAS metabolites allyl hydropolysulfides have been detected in vitro and in vivo in the Gram positive bacterium Bacillus subtilis. …
-
Fabrication, analysis, application, and characterization of core-containing microparticles and hydrophilic microfluidic devices produced via the primary- and in situ tertiary-amine catalyzed Michael addition of multifunctional thiols to multifunctional acrylates
The objective of this research was to investigate amine-catalyzed thiol-acrylate chemistry for various novel applications that could fully utilize the untapped potential of this useful and robust chemistry. The use of this chemistry in each application solved a problem, improved on a disadvantage …
-
The Binding of the Micronutrient Transition Metals to the Alkylation Products of Chemical Warfare Agent, Sulfur Mustard, and Thiols, Potentially Giving New Understanding to Physiological Effects of Exposure and Increased Toxicity
<p>Model compounds, 3,6,9-trithaiundecane-1,11-dicarboxylic acid (TTDPA), 2,5,8-trithianonane-1,9-dicarboxylic acid (TTDAA), and 1,11-diamide-3,6,9-trithiaundecane (TTDAce), closely related to the adducts formed by cysteine alkylation of the chemical weapon, sulfur mustard, were synthesized. It is …
-
Dechalcogenative Allylic Selenosulfide And Disulfide Rearrangements For Cysteine Modification And Glycoligation
… for the permanent functionalization of thiols, and in particular of cysteine and carbohydrate based thiols. Emphasis is placed on the newly invented silver mediated allylic desulfurative rearrangement for the primary modification of thiols and the synthesis of complex oligosaccharide …
-
Biosynthetic and Functional Studies of Bacillithiol in Gram-positive Bacteria
Low-molecular-weight (LMW) thiols play vital roles on a variety of cell metabolic pathways including oxidative stress management, xenobiotic detoxification, post-translational modification, and metal homeostasis. Previous studies have identified glutathione (GSH) as the dominant LMW thiol in …
-
Kinetic analysis of thiol oxidation to study the effects of fluorinated groups on metal phthalocyanine catalysts
… and industrially. Corrosive and malodorous thiols exist as contaminants in wastewater discharge from mining facilities, pulp and paper mills, tanneries, and oil refineries. The elimination of thiols from petroleum products is necessary for even cleaner fuels. Thiols in gas products can also …
-
A role for glutathione in reactions between oxidants and proteins
… The pure protein was modified on multiple thiols when incubated with thiol oxidants. H2O2 + GSH was found to S-glutathiolate H-Ras on at least one cysteine, while either diamide + GSH or glutathione disulfide (GSSG) was found to S-glutathiolate at least two H-Ras cysteines. The NO donor …
Page 1 of 8