Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 82 for “"Thiolate"”.
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Structural Analysis Of Bulky Thiolate-Protected Gold Nanomolecules
Routine preparation of thiolate-protected gold nanomolecules involves, most commonly, straight-chain organic thiolate ligands for which the sulfhydryl `head' group is bound to a primary carbon atom. The primary connectivity of these sulfur atoms, such as for the case of n-hexanethiol and …
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Metal Thiolate and Metal Sufide Clusters in Proteins
Finally efforts towards the design of a biosynthetic model of Cu Z from N2OR are reported. The CuZ cluster is the first and only report to date of a copper-sulfide cluster in Nature. It fulfills a catalytic role in N2OR, performing the reduction of N2O to N2 and H2O during anaerobic respiration, …
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The synthesis and reactivity of thiolate bridged diiron hexacarbonyl complexes
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1987.
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Ligand Effect on Gold Nanomolecules Demonstrated Using Aliphatic, Aromatic and Bulky Thiolate Ligands
Atomically precise thiolate protected gold nanoparticles (AuNPs) known as gold nanomolecules (AuNMs) are intensely pursued owing to their feasibility to elucidate their structure by single crystal X-ray crystallography. They have distinct number of Au atoms (n) and thiolate (-SR, R-hydrocarbon …
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The detection of nitric oxide and its reactivity with transition metal thiolate complexes
… redox active units, such as transition metals or thiolate ligands. To gain insight into how NO might regulate biological processes by interacting with these redox active species, we have initiated a fundamental study of the reactivity of NO with transition metal thiolate model complexes. Our …
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Thiolate self-assembled monolayers studied with a tuneable infrared low temperature laser driven scanning tunnelling microscope
… surface features are observed in the octanethiolate monolayers. The results of STS experiments with an octanethiolate monolayer reveal correlations between surface features and conductivity at -1.0V. The differences between these STS data and equivalents from uncoated samples reveal the …
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Synthesis, characterization, and anticancer evaluation of novel gold(I) phosphine thiolate complexes : solubility, cellular uptake, and cytotoxicity.
… and evaluation of novel gold(I) phosphine thiolate complexes as potential anticancer agents. Inspired by the activity of auranofin and the limitations of existing platinum-based drugs such as cisplatin, this research sought to explore the therapeutic potential of systematically varied …
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Cyclometallated platinum and iridium complexes with thiolate ligands, and novel bioimaging agents inspired by dynamic disulfide interchange reactions
… n = 0,1) is described and their reactions with thiolates are explored with the aim of producing new classes of thiol sensors. Thus, novel monometallic complexes of the type [Pt(N^C^N)(thiolate)] and [Ir(N^C^N)(N^C)(thiolate)] are reported as well as a novel series of dimers with the general …
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The Electrochemistry of Ferrocenyl-thiolate Self-Assembled Monolayers for use in a Toll-like Receptor 4-based sensor
… are surface immobilized via ternary alkanethiolate self-assembled monolayers (SAMs) deposited on polycrystalline Au surfaces. These SAMs possess a uniquely low interfacial resistance (? 1 k?) due to the presence of a Ferrocenyl-thiolate component, which mediates electron transfer from …
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Investigating the Interactions Between the Thiolate Ligand and Mutants of a Conserved Tryptophan in the Proximal Heme Pocket of the Oxygenase Domains of Endothelial and Staphyloccus Aureus Nitric Oxide Synthases
The electronegativity of thiolate ligation in the hemeprotein nitric oxide synthase (NOS) proteins has been identified as an influence on autoinhibition in this enzyme. The mutation of a conserved tryptophan residue, which hydrogen bonds to the coordinating thiolate ligand and therefore influences …
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An Organometallic Approach to Iron Triazacyclononane Coordination Complexes
… active site of NiFe hydrogenase features a bis(thiolate) bridged nickel-iron site, where the iron is bound to two carbonyls and a cyanide. The reaction of the square planar Ni(N2S2), where (N2S2)2- = -SCH2CH2N(Me)CH2CH 2N(Me)CH2CH2S- and (Me 3TACN)FeCl2 gives [Ni(N2S2)FeCl(Me3TACN)](BPh 4), a …
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Characterization of the Active Site of Chloroperoxidase Using Physical Techniques (Hemeproteins)
… several techniques. Recent work has demonstrated thiolate ligation from a cysteine residue to the iron in P-450. A major portion of my research has been devoted to obtaining direct evidence that CPO also has a thiolate 5th ligand from a cysteine residue. This information will provide the framework …
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Synthesis and Coordination Complexes of Bis-Pocket Siloxyporphyrins
A high yield synthetic route for an alkylthiolate-tailed bis-face protected iron porphyrin was developed. The high stability of this compound is likely due to the protection from the siloxy pocket around the thiolate tail. Very similar rhombic, high spin EPR spectra for this model compound and the …
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Metal Chalcogenide Nanocrystal Assembly: From Synthesis To Applications
… by sol-gel assembly of CdTe nanocrystals with thiolate or nonthiolate (phosphine oxide) ligated surfaces by treatment with tetranitromethane. Both phosphine oxide-capped and the thiolate-capped aerogels exhibit similar structure, morphology and porosimetry properties, suggesting that precursor …
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High-oxidation-state molybdenum and tungsten monoalkoxide pyrrolide alkylidenes as catalysts for olefin metathesis
… 4 contains synthetic and catalytic studies of thiolate-containing Mo and W imido alkylidene complexes. The species M(NAr)(CHCMe 2Ph)(pyr)(SHMT) (M = Mo or W), Mo(NAr)(CHCMe₂Ph)(Me₂pyr)(STPP), and Mo(NAr)(CHCMe₂Ph)(STPP)₂ are synthesized by substitution of the appropriate thiol or thiolate …
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Charge-Transfer Complexes for Amine Synthesis
… charge-transfer complex between iminium and thiolate ions. DFT calculations indicated that irradiation of the complex with visible light could promote intra-complex electron transfer from the thiolate HOMO to the iminium LUMO. This method of α-amino radical formation was extended to acyclic …
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Studies of Reaction Mechanisms Requiring Low Molecular Weight Thiol Cofactors
… bond rather than the nucleophilic attack by thiolate anion which has been pro
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Gold Nanomolecules : Developing Synthetic Protocols, Characterization And Investigation Of Ligand Effects On Structure And Properties
… atmospheric conditions and most chemicals. Gold thiolate nanomolecules, which is the primary focus of this dissertation research, are chemical molecules with a fixed number of gold atoms and organo-thiolate ligands. They are of the form Aux(SR)y and possess molecule-like properties as a result of …
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