Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Thiol Antioxidant"”.
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The maculoprotective effect of a thiol antioxidant in retinal degeneration models
… of AMD, clinical studies have shown that dietary antioxidants can delay progression of AMD. Currently, there is no FDA-approved treatment for AMD. Therefore, we hypothesized that N-acetylcysteine amide (NACA), a thiol antioxidant, would protect retinal pigment epithelium and impede the progression …
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A study of the beneficial role of thiol antioxidant supplementation in various forms of glutathione deficiency
… are on the constant lookout for new and better antioxidants that have the ability to slow, if not stop the harmful degenerative effects of free radicals in oxidative stress related disorders. Both synthetic and naturally occurring compounds are being constantly screened for their antioxidant …
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Role of glutamate in lead-induced toxicity: protection by N-acetylcysteine amide (NACA), a novel thiol antioxidant
"Despite several efforts to reduce lead levels in the environment, lead exposure continues to be a major public health problem, in the US today. Toxic effect of lead are mainly manifested in central nervous system (CNS) because brain acts as a reservoir for lead deposition. Lead-induced cell damage …
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Oral epithelium in the pathogenesis of periodontitis
… epithelial response using a natural di-thiol antioxidant \(\alpha\)-lipoate was also investigated. Data demonstrated that periodontal pathogens P. gingivalis and F. nucleatum elicited a pro-inflammatory response in the H400 model system. This was confirmed by demonstrating NF-\(\kappa\)B …
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Effects of n-acetylcysteine amide in preventing/treating cataracts
… study has sought to evaluate the efficacy of a thiol antioxidant, (R) -N-acetylcysteine amide (NACA), in preventing/reversing cataracts. To investigate NACA's ability to provide therapeutic benefits for cataracts, three different experimental models were utilized. The first was an ex-vivo …