Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Thiazoles"”.
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Synthesis and reactions of some thiazoles ; Thio-urea preparations
Includes bibliographical references.
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Design, synthesis and characterization of thiazole-based conjugated polymers and their applications to n-channel organic electronics
… solar cells. Among many electron-poor units, thiazoles stand out as a promising building block for high performance organic semiconductors. This dissertation discusses the development of thiazole-based π-conjugated semiconducting polymers to enhance the electron field-effect mobilities by …
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Synthesis and characterization of Ir(III) metallacycles derived from thiophene and related compounds: models for the hydrodesulfurization process
… to [Ir(COD)(PMe3)3]CI, nitrogen present in the thiazoles exhibit enhanced nucleophilicity. For exmnple, compounds II-IV react with methylene chloride to form dimers: CH2[NCR=CR'SIr(Cl)(PMe3)3CH]2. The above compounds are soluble in water and react with PF6 salts liberating the chloride atom from …
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Biosynthetic engineering of plantazolicin natural products
… then oxidizes most of these azolines to thiazoles and (methyl)oxazoles. The final biosynthetic steps consist of leader peptide removal and dimethylation of the nascent N-terminus. To simultaneously establish the structure-activity relationship of PZN and the substrate tolerance of the …
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Structure and function analysis of the natural product plantazolicin, a bacillus anthracis-specific antibiotic
… and post-translationally modified to contain thiazoles and (methyl)oxazoles. This group of compounds, known as thiazole/oxazole-modified microcins (TOMMs), exhibit disparate biological activities and complex chemical structures. Using high-resolution mass spectrometry, chemoselective …
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Palladium-catalyzed C-N cross-coupling and application to the synthesis of delayed singlet emitters for OLED development
… access to Narylated imidazoles, pyrazoles, thiazoles, pyrroles, and thiophenes in moderate to excellent yield. Experimental results and DFT calculations point to the need for electronrich and especially sterically demanding biaryl dialkylphosphine ligands to promote these difficult …
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Structural and biochemical studies on tailoring enzymes involved in ribosomal peptides biosynthesis
… or asymbiotic cyanobacteria. They contain rigid thiazoles and/or (methyl)oxazoles similar to LAP and additional head-to-tail cyclization on backbone to decrease its flexibility and susceptibility to proteases. Many cyanobactins are subsequently decorated with isoprenoid groups on Tyr, Ser or Thr …
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ANTIMICROBIAL CHARACTERIZATION AND THERAPEUTIC APPLICATIONS OF NOVEL SYNTHETIC THIAZOLE COMPOUNDS AGAINST MULTIDRUG-RESISTANT STAPHYLOCOCCI AND ENTEROCOCCI
… whole-cell screening of libraries of substituted thiazoles and thiadiazoles. Subsequent derivatives were constructed in an attempt to enhance potency, decrease toxicity to host tissues, and improve the lead compound’s drug-like properties. Broth microdilution assay results show that the lead 1 and …
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Spécificité mutationnelle du 2-formylamino 4-(5-nitro 2 furyl) thiazole dans le gène lacI d'escherichia coli
Afin de mieux comprendre la spécificité mutationnelle des 5-nitrofuranes, nous avons étudié les mutations induites par le 2-formylamino-4-(5-nitro-2-furyl) thiazol (FANFT), un 5-nitrofurane, dans la région NC+ du gène lacl d’Escherichia coli. Le traitement de la souche TC3960 avec 50 |nM de FANFT …
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THE ROLE OF NRF2 IN PREVENTING OXIDATIVE/ELECTROPHILIC STRESS-INDUCED LIVER INJURY
… (diaryl amides and diaryl ureas, oxazoles and thiazoles, pyranones and thiapyranones, and pyridinones and pyridazinones). The top 30 compounds were screened in Hepa1c1c7 cells to increase Nqo1 mRNA, the prototypical Nrf2 target gene, and 17 of the 30 most active hits also increased Nqo1 mRNA in …