NDLTD logo NDLTD Union Catalog and Global ETD Search

Global ETD Search

Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

Results

Showing 1 to 20 of 23 for “"Thermotoga maritima"”.

  1. Charakterisierung thermophiler Cellulasen aus Sulfolobus solfataricus und Thermotoga maritima

    Kufner, KristinaUniversität Bayreuth

    … im aktiven Zentrum ausgewählt. CelA aus Thermotoga maritima und EglA aus Pyrococcus furiosus wurden bereits in früheren Arbeiten charakterisiert und weisen ebenfalls extreme Hitzestabilität auf mit einem pH-Optimum im leicht sauren Bereich bei pH 6. Durch gezielten Austausch von …

    bayreuth Repository record

  2. Biochemical and structural characterization of Sirtuins from mammals and Thermotoga maritima

    Lakshminarasimhan, MahadevanUniversität Bayreuth

    … and play a role in the enzyme’s activity. The thermotoga maritima Sirtuin Sir2Tm was used as a model system for structural characterization of Sirt1. The crystal structure of Sir2Tm in complex with Ex-527, a potent Sirt1 inhibitor was solved, which combined with biophysical studies offers …

    bayreuth Repository record

  3. Molekulare, biochemische und strukturelle Untersuchungen an amylolytischen Enzymen von Thermotoga maritima MSB8

    Raasch, Carsten2012

    Das hyperthermophile Bakterium Thermotoga maritima MSB8 (Wachstumsbereich: 55°C - 90°C) ist eines der thermophilsten und ursprünglichsten aller bisher bekannten Mikroorganismen und verwertet durch einen fermentativen Stoffwechsel organische Polymere wie z.B. Stärke. An diesem Prozeß sind …

    goettingen Repository record

  4. The organization, expression, function and evolution of some essential genes from the hyperthermophilic eubacterium thermotoga maritima

    Liao, DaiqingUniversity of British Columbia1993

    The hyperthermophilic eubacterium Thermotoga maritima grows optimally at 80°C near marine geothermal locales. Phylogenetic analyses based on various molecular sequences indicate that T. maritima and other hyperthermophilic prokaryotes have very deep phylogenetic placements; i.e., that they have …

    ubc Repository record

  5. Directed evolution of novel properties starting from HisF of <i>Thermotoga maritima</i> as a structural scaffold

    Ling, Zhenlian2012

    … aus dem hyperthermophilen Organismus T. maritima mit der Struktur einer (βα)8-Barrels, wurde als Gerüst für eine direkte Evolution von Enzymen genutzt. Die thisF-Genbibliotheken wurden durch teilweises Randomisieren von Zielpositionen im thisF-Gen im Phagemid-Vektor pCANTAB 5E und im …

    goettingen Repository record

  6. Präparation und röntgenkristallographische Untersuchungen an archaebakteriellen Box C/D sRNPs und einer neuartigen Glukosyltransferase aus Thermotoga maritima MSB8

    Steinke, Carmen2012

    … im Jahr 1998 identifizierte Enzym Amylase B aus Thermotoga maritima MSB8 wurde aufgrund seiner Fähigkeit, Stärke und deren Abbauprodukte Amylose und Amylopektin an den α-1,4-glykosidischen Bindungen zu spalten, als α-Amylase deklariert. Eine Einordnung der Amylase B in die Glykosyl-Hydrolase …

    goettingen Repository record

  7. Versuche zur Strukturaufklärung bakterieller Thiouridin Synthetasen

    Naumann, Peter-Thomas2012

    … aus Escherichia coli und dem Hyperthermophilen Thermotoga maritima sollte aufgeklärt werden. Dazu wurden die entsprechenden Gene in Escherichia coli kloniert und exprimiert. Es war möglich, Aufreinigungs-protokolle für die verschiedenen Proteine zu etablieren. Bei den nachfolgenden …

    goettingen Repository record

  8. Assignment of Enzyme Function Through Characterization of the RuBisCO and Enolase Superfamilies

    Imker, Heidi J.University of Illinois at Urbana-Champaign2015

    … are varied. Two highly divergent enzymes from Thermotoga maritima and Enterococcus faecalis were targeted for characterization through a multi-disciplinary effort that included structural, computational, and bioinformatic analysis as well as classical enzymology. The T. maritima and E. faecalis …

    uiuc Repository record

  9. STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF THE BACTERIAL FLAGELLAR MOTOR HOOK COMPLEX AND THE MS:C-RING INTERFACE

    Lynch, Michael JosephCornell University2019

    … complex from the representative thermophile Thermotoga maritima. The FliFC:FliGN complex reported here has subsequently been reproduced in a crystal structure of the same complex from H. pylori. Comparison of the two complexes reveal that they are essentially identical, owing to the universal …

    cornell Repository record

  10. Vergleichende biochemische und strukturelle Untersuchung thermophiler α-Amylasen

    Ballschmiter, Meike2012

    … AmyB-Tm aus dem hyperthermophilen Bakterium Thermotoga maritima, AmyB-Tt aus dem extrem thermophilen Bakterium Thermus thermophilus und AmyA-Ag sowie AmyB-Ag aus dem thermoalkaliphilen Bakterium Anaerobranca gottschalkii, untersucht. Der Schwerpunkt lag dabei auf dem Enzym aus T. maritima. …

    goettingen Repository record

  11. Enzymatic Production of Cellulosic Hydrogen by Cell-free Synthetic Pathway Biotransformation(SyPaB)

    Ye, XinhaoVirginia Tech2011

    … carbohydrate-binding module (CBM) family 9 from Thermotoga maritima Xyn10A. The inactivation halftime of C. thermocellum cellobiose phosphorylase has been enhanced by three-fold at 70°C via a combination of rational design and directed evolution. The phosphorylases with improved properties would …

    vt Repository record

  12. Development of Building Blocks - Thermostable Enzymes for Synthetic Pathway Biotransformation (SyPaB)

    Sun, FangfangVirginia Tech2012

    … phosphate pathway, was cloned from a thermophile Thermotoga maritima, and heterologously expressed in Escherichia coli, purified and characterized. High-purity RpiB was obtained by heat pretreatment through its optimization in buffer choice, buffer pH, as well as temperature and duration of …

    vt Repository record

  13. Characterization of Mycobacterium tuberculosis Cor, a Protein Essential for Carbon Monoxide Resistance and Pathogenesis

    Zacharia, Vineetha MariamUT Southwestern Medical Center2015

    … expression of Cor and Cor homologue from Thermotoga maritima (TM0160) in Escherichia coli rescued it from CO toxicity, suggesting a conserved function across diverse microbial species. Importantly, the virulence of the cor mutant is attenuated in a mouse model of tuberculosis. Thus, Cor is …

    utswmed Repository record

  14. Pervasive degeneracy and epistasis in a protein-protein interface

    Podgornaia, Anna IgorevnaMassachusetts Institute of Technology2014

    … mutagenesis study of a two-component system from Thermotoga maritima that has proven amenable to structural analysis. By solving the cocrystal structure of a histidine kinase and response regulator containing interface residues from a different interacting pair, we learned the biophysical basis …

    mit Repository record

  15. Gene finding and the evaluation of synonymous codon usage features in microbial genomes

    McHardy, Alice CarolynUniversität Bielefeld

    … für das Genom des hyperthermophilen Bakteriums Thermotoga maritima durchgeführt, welches Genregionen von vermutlich archaebakteriellem Ursprung enthält. Die mit der neuen Methode gefundenen Ergebnisse stehen im Einklang mit den Ergebnissen von früheren phylogenetischen und strukturellen Analysen …

    bielefeld Repository record

  16. Mechanistic investigations of class III anaerobic ribonucleotide reductases

    Wei, Yifeng, Ph. D. Massachusetts Institute of TechnologyMassachusetts Institute of Technology2015

    … based on a crystal structure of the homologous Thermotoga maritima enzyme showed conserved residues appropriately positioned to carry out chemistry. Phylogenetic studies suggest that NrdD2 is present in bacteria and archaea that carry out diverse types of anaerobic metabolism. The bioinformatics …

    mit Repository record

  17. Biohydrogen as a Fuel: Understanding and Engineering Hydrogenase Enzymes for Biotechnological Applications

    Lamont, Ciaran MitchellUniversity of Dundee2016

    … between E. coli Hyd-3 and a ferredoxin from Thermotoga maritima, was characterised and shown to exhibit in vivo H2 evolution when co-produced with a heterologous pyruvate: ferredoxin oxidoreductase. This allowed pyruvate to be employed as a new electron donor for H2 production. In addition, …

    dundee Repository record

  18. Molecular modeling and simulation of bacterial chemosensory arrays

    Cassidy, C. KeithUniversity of Illinois at Urbana-Champaign2017

    … portion of the chemosensory array from Thermotoga maritima is constructed and refined. Through the use of large-scale MD simulations, a novel conformational change in a key signaling protein is identified and subsequently shown to be critical for chemotaxis signaling in live E. coli …

    uiuc Repository record

  19. Structural Analysis of the 50S Ribosomal Stalk

    Diaconu, Mihaela Stefania2012

    … NTD des L12 aus dem hyperthermophilen Bakterium Thermotoga maritima. In den drei gewonnen Kristallstrukturen wies L10 eine globuläre NTD auf, welche über einen flexiblen Loop mit einer langen C-terminalen α-Helix verbunden war. Die Helix zeigte in verschieden Kristallformen unterschiedliche …

    goettingen Repository record

  20. NMR application and development : study of the ribosomal RNA-L11 complex

    Ilin, Serge, 1977-Massachusetts Institute of Technology2005

    … L11 protein from the thermophilic eubacterium Thermotoga maritima in its free form was solved, the binary complex of L 11 protein with RNA and the N-terminal domain alignment were investigated, the possible inhibition mode of the L11-RNA complex by thiostrepton was proposed and studies aimed at …

    mit Repository record

Page 1 of 2