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Showing 1 to 20 of 49 for “"Thermosensitive"”.
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Structure, Dynamics and Association of Thermosensitive Core-Shell Particles
… characterization, dynamics and association of thermosensitive core-shell particles. The particles consist of a solid core of poly(styrene) with a thin layer of poly(N-isopropylacrylamide) (PNIPAM) onto which a network of PNIPAM is affixed. The degree of crosslinking of the PNIPAM shell effected …
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Synthesis and characterization of thermosensitive hydrogels derived from polysaccharides
In this work, thermosensitive hydrogels having tunable thermo-mechanical properties were synthesized. Generally the thermal transition of thermosensitive hydrogels is based on either a lower critical solution temperature (LCST) or critical micelle concentration/ temperature (CMC/ CMT). The …
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Design of Thermosensitive Hydrogel for Extended-Release of Praziquantel
… this study aimed to develop an extended-release thermosensitive hydrogel formulation that was applicable to the injectable administration. The praziquantel-loaded hydrogel formulation based on poloxamer 407 (20%, w/v) was prepared, and two strategies for modifications of poloxamer 407 hydrogel …
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Development of Novel Thermosensitive Polymers for Bioresponsive Drug Delivery
… thermogels. Taken all together, the novel thermosensitive polymers and nanocomposite thermogel system have great potential for bioresponsive local drug delivery where the amount of bioactive release entirely depends on physiological needs.
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Characterization of Thermosensitive Preoptic Neurons in the Green Sunfish, Lepomis Cyanellus
(1) The local thermosensitivities of 276 neurons in the preoptic region of green sunfish acclimated to 25(DEGREES)C were obtained using extracellular recording techniques and classified into 5 basic types. Type 1 neurons, which comprised 4% of the total, had low firing rates (approximately …
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An Injectable Thermosensitive Hydrogel Potentially Used for Wound Dressing with Self-adhesive Properties
… pH, temperature, light, ions in body fluids. Thermosensitive hydrogel is commonly used due to its high retention of cells and drugs in the local sites. Poly (N-Isopropylacrylamide) (PNIPAM) could be applied because PNIPAM-based polymers can achieve fast gelling at body temperature. …
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Thermosensitive Characteristics of Preoptic Area Neurons in the New Zealand White Rabbit, Oryctolagus Cuniculus
Made available in DSpace on 2014-12-14T13:39:37Z (GMT). No. of bitstreams: 1 7616185.pdf: 3078385 bytes, checksum: 635195762727e57c449cf840fe356138 (MD5) Previous issue date: 1976
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Thermosensitive Injectable Pluronic Hydrogels for Controlled Drug Release: Characterisation of thermal, rheological and structural properties of injectable pharmaceutical formulations
This study seeks to develop smart hydrogel formulations for injectable controlled drug delivery from Pluronics to enhance patients compliance, decrease side effects, reduce dose and frequency. A biocompatible copolymer, Pluronic F127 was probed as the main ingredient for the injectable systems …
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Thermosensitive Injectable Pluronic Hydrogels for Controlled Drug Release: Characterisation of thermal, rheological and structural properties of injectable pharmaceutical formulations
This study seeks to develop smart hydrogel formulations for injectable controlled drug delivery from Pluronics to enhance patients compliance, decrease side effects, reduce dose and frequency. A biocompatible copolymer, Pluronic F127 was probed as the main ingredient for the injectable systems …
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Smart Materials for Cartilage and Bone Tissue Engineering
… thesis, a variety of smart materials, such as thermosensitive poly (N-isopropylacrylamide-acrylic acid) hydrogel and magnetic field-responsive scaffold, were fabricated, characterized, and utilized for three-dimensional (3D) culture of mesenchymal stem/stromal cells (MSCs) in vitro. It was …
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Synthesis and characterization of platinum(II) loaded thermosensitive poly(vinyl ether)s and investigations into their potential as UV-triggerable hydrosilylation catalysts
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Pentablock copolymers based controlled release formulations of small and macromolecules for ophthalmic applications
… developed for fabrication of nanoparticles and thermosensitive hydrogel formulations for long term delivery of small and macromolecules. Different pentablock copolymer compositions were evaluated to optimize drug release profile from nanoparticles and thermosensitive gel formulations. Our …
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Solution Properties of Polymer Nanostructures Studied by Scattering Techniques
… polymer brushes, dendronized polymers and the thermosensitive microgel systems. The work comprises of different polymer nanostructured systems mainly studied by using the scattering techniques at the solution state . The importance of the studying the solution properties of the polymer systems …
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Topical Nanoparticulate Formulation of Drugs for Ocular Keratitis
… (DLGCV) were formulated and dispersed in thermosensitive PLGA-PEG-PLGA polymer gel for the treatment of herpes simplex virus type 1 (HSV-1) induced viral corneal keratitis. NP containing prodrugs of GCV were prepared by a doubleemulsion solvent evaporation technique using various PLGA …
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Co-polymer microgels: contemporary physico-chemical, structural and analytical investigations
Poly(N-isopropylacrylamide), [poly(NIPAM)], is a thermosensitive polymer which undergoes a conformational transition at approximately 32°C in aqueous solution. NIPAM is a monomer commonly employed in microgel synthesis and the resultant particles are thermosensitive, a property which can be altered …
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Implicaciones de la NDP reductasa en la progresión de las horquillas de replicación en Escherichia coli
… progression in a nrdA101 mutant, which has a thermosensitive NDP reductase. We have proved that the Nucleotides Synthesis Complex and the Replication Complex are associated in a Replication Hyperstructure.
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Development of polymeric nanoparticulate formulation encapsulating protein molecules following hydrophobic ion pairing complexation
… Further, nanoparticles were suspended in thermosensitive gel to achieve sustained release. HIP complexation has provided sustained release of protein from nanoparticles suspended in thermosensitive gel. Released protein maintained their physical stability and biological activity. No …
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Synthesis and self-assembly of multiple thermoresponsive amphiphilic block copolymers
… proton NMR spectrum. First a set of double thermosensitive diblock copolymers poly(N-n-propylacrylamide)-b-poly(N-ethylacrylamide) was synthesized which differed only in the relative size of the two blocks. Depending on the relative block lengths, different aggregation pathways were found. …
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