Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Thermal Therapy"”.
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Quantitative ultrasound assessment of thermal therapy in liver
… In this work, the potential of QUS to assess thermal therapy in liver tissue was examined. Specifically, the QUS parameters of attenuation slope, effective scatterer size (ESD), effective acoustic concentration (EAC), and envelope statistics parameters μ and k were evaluated with respect to …
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Dynamic Chemical Shift Imaging For Image-Guided Thermal Therapy
… to provide temperature imaging for guidance in thermal therapies. The most common method of estimating temperature changes in the body using MR is by measuring the water proton resonant frequency (PRF) shift. Calculation of the complex phase difference (CPD) is the method of choice for measuring …
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Feasibility Study of Multi-application, Multi-Walled Carbon Nanotube for Magnetic Resonance Temperatrue Imaging Guided Laser Induced Thermal Therapy
… improve the safety and efficacy of Laser Induced Thermal Therapy (LITT). Instilled MWCNTs enable precise tumor localization and killing of the tumor through preferential high temperature while protecting surrounding healthy tissue by monitoring the 3D temperature distribution. As advanced MR …
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Synthesis, surface modifications and biomedical applications of colloidal gold nanoparticles, towards controlled regulation of angiogenesis in conjunction with photo-thermal therapy
… enables their usage in a number of imaging and therapy techniques. Biological activity of NPs is determined by the chemical composition of the organic corona, surrounding the gold core. Appropriate surface capping provides NPs with substantial stability against aggregation (and loss of their …
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PRECLINICAL DEVELOPMENT OF CARBON NANOTUBE MEDIATED THERMAL THERAPY FOR TREATMENT OF GLIOBLASTOMA MULTIFORME: DETERMINING THE EFFECTS OF NANOMATERIAL PROPERTIES, DOSE, AND IRRADIATION PARAMETERS ON THE EFFICACY AND POTENTIAL NEGATIVE REPERCUSSIONS OF TREATMENT
… clinic, physicians are using Laser Interstitial Thermal Therapy (LITT) to treat such tumors. Previous studies, including my own, have shown the addition of carbon nanotubes (CNTs) in combination with laser energy increases the rate to heat deposition, achieving much higher temperatures at a much …
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Nanoparticle preconditioning for enhanced thermal therapies in cancer.
… of molecular adjuvants to enhance local cancer therapy. One important form of local cancer treatment that suffers from local recurrence and distant metastases is thermal therapy. A new concept involving the use of nanoparticle-delivered adjuvants to `precondition' (alter the vascular and …
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Determination of Thermal Dose Model Parameters Using Magnetic Resonance Imaging
… monitoring temperature during minimally invasive thermal therapy procedures. When coupled with thermal dose models, MRTI feedback provides the clinician with a real-time estimate of tissue damage by functioning as a surrogate for post-treatment verification imaging. This aids in maximizing the …
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Optimized pulsing of high-intensity focused ultrasound for enhanced therapeutic window
… modality to perform non-invasive surgeries. The thermal ablation technique relies on focusing the non-ionizing acoustic wave within soft tissues to produce a small lesion. HIFU operations are typically attempted by continuous-wave (CW) applications of the beam intervened by wait periods to allow …
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Non-invasive in vivo ultrasound temperature estimation
New emerging technologies in thermal therapy require precise monitoring and control of the delivered thermal dose in a variety of situations. The therapeutic temperature changes in target tissues range from few degrees for releasing chemotherapy drugs encapsulated in the thermosensitive liposomes …
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THERMA KRANJI : RAMMED EARTH IN SINGAPORE
The proposed project is a thermal therapy resort which is inspired from the sustainable characteristic of rammed earth. In the current global context, architecture is often one of a linear process and generates waste through its processes and operations. The proposed project is one, inspired from …
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Materials, device designs, and integration approaches for transient, bio-resorbable silicon electronic systems
… A transient silicon device capable of delivering thermal therapy in an implantable mode and its demonstration in animal models illustrate a system-level example of this technology. Another discovery for this type of transient electronics is materials and fabrication procedures that the key device …
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Interaction of Nanoparticles with RF, AC, and Static Magnetic Fields in Thermal and Non-Thermal Cancer Therapy Applications
… the complex problem of targeted cancer therapy. Thermal therapies such as radio-frequency and microwave hyperthermia and ablation techniques though effective in ablating tumors are non-target specific. The dissertation focus on alternate thermal and non-thermal approaches inducing cancer …
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Real-time Temperature Imaging Using Ultrasonic Change in Backscattered Energy
<p>Thermal therapy from low-temperature cryosurgery to high-temperature ablation of tumors and unwanted electrical pathways has gained increased attention. Temperature imaging (TI) from magnetic resonance studies is the de facto standard for volumetric estimation of temperature. Ultrasound has the …
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Ultrasound stimulated acoustic emission for monitoring thermal surgery
… on MRI techniques to monitor the extent of the thermal surgery. Besides for the great cost and limited availability, MRI monitoring presents limitations for therapeutic equipment design because all other equipment must be compatible with the large magnetic fields created by the MRI system. A new …
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Prediction of Laser Ablation In Brain: Sensitivity, Calibration, and Validation
… surgical planning of MR-guided laser induced thermal therapy (MRgLITT) stands to benefit from predictive computational modeling. The dearth of physical model parameter data leads to modeling uncertainty. This work implements a well-accepted framework with three key steps for model-building: …
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Measuring Nonlinear Properties of Graphene Thin Films Using Z-Scan Technique
… as an excellent heat spreader due to its high thermal conductivity. However, the experimental nonlinear study of graphene materials and their application in developing future optoelectronic devices demands for more developed research.</p> <p>The research objective is first to build a precise, …
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Stochastic Data Assimilation Approaches For Magnetic Resonance Temperature Imaging
<p>During magnetic resonance (MR)-guided thermal therapies, proton resonance frequency shift (PRFS) based MR temperature imaging can quantitatively monitor tissue temperature changes. It is widely known that the PRFS technique is easily perturbed by tissue motion, tissue susceptibility changes, …
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Validation Platform for Ultrasound-Based Monitoring of Thermal Ablation
PURPOSE: Thermal ablation therapy is an emerging local cancer treatment to destroy cancer tissue using heat. However variations in blood flow and energy absorption rates make it extremely challenging to monitor thermal changes. Insufficient ablation may lead to recurrence of the cancer while …
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Effects of high intensity focused ultrasound on the intervertebral disc
The purpose of this study was to study and try to optimise high intensity focused ultrasound treatment of the intervertebral disc. We demonstrated that it was possible to heat intervertebral discs with HIFU delivered by 50 or 5 mm diameter ultrasound transducers. Finite element studies indicated …
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Harnessing the optical properties of gold nanorods: fluorescence enhancement, biosensing and photothermal therapy
… sensing, bioimaging, drug delivery, and cancer therapy. Excitation of a gold nanorod localized surface plasmon resonance (LSPR) can result in the enhancement of many photophysical processes such as light absorption, Rayleigh (Mie) scattering, and fluorescence. The presence of a strong …