Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Thermal Therapies"”.
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Intracavitary ultrasound phased arrays for thermal therapies
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1997.
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Nanoparticle preconditioning for enhanced thermal therapies in cancer.
… from local recurrence and distant metastases is thermal therapy. A new concept involving the use of nanoparticle-delivered adjuvants to `precondition' (alter the vascular and immunological biology) tumors to enhance their susceptibility to thermal therapy has been developed in our lab. Previous …
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Stochastic Data Assimilation Approaches For Magnetic Resonance Temperature Imaging
<p>During magnetic resonance (MR)-guided thermal therapies, proton resonance frequency shift (PRFS) based MR temperature imaging can quantitatively monitor tissue temperature changes. It is widely known that the PRFS technique is easily perturbed by tissue motion, tissue susceptibility changes, …
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Dynamic Chemical Shift Imaging For Image-Guided Thermal Therapy
… to provide temperature imaging for guidance in thermal therapies. The most common method of estimating temperature changes in the body using MR is by measuring the water proton resonant frequency (PRF) shift. Calculation of the complex phase difference (CPD) is the method of choice for measuring …
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Temperature Mapping using Mid-Field Magnetic Resonance Imaging
… these <1T >systems, which can be used to monitor thermal therapies interventionally. This thesis addresses the potentials for implementing temperature mapping at 0.5T, both in the creation of a tissue mimicking phantom which can be used to compare temperature mapping methods and implementing …
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Cell Death Characterization In Tumor Constructs Using Irreversible Electroporation
… Irreversible electroporation is a new non-thermal focal ablation therapy utilizing short, pulsed electric fields to damage cell membranes leading to cell death. The therapy is minimally invasive, involving the insertion of needle electrodes into the region of interest and lasts less than …
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Cavitation methods in therapeutic ultrasound : techniques, mechanisms, and system design
… is currently being developed as a non-invasive thermal ablation technique for benign and cancerous tumors in several organ systems. Although these therapies are designed to ablate tissue purely by thermal means, cavitation, the formation and collapse of gas bubbles, can occur. These bubbles can …
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Measurement of tissue optical properties during mechanical compression using swept source optical coherence tomography
Laser-based photo-thermal therapies can provide minimally-invasive treatment of cancers. Their effectiveness is limited by light penetration depth in tissue due to its highly scattering properties. The highly disordered refractive index distribution in tissue leads to multiple-scattering of …
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Interaction of Nanoparticles with RF, AC, and Static Magnetic Fields in Thermal and Non-Thermal Cancer Therapy Applications
… the complex problem of targeted cancer therapy. Thermal therapies such as radio-frequency and microwave hyperthermia and ablation techniques though effective in ablating tumors are non-target specific. The dissertation focus on alternate thermal and non-thermal approaches inducing cancer cell …
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Modeling of carbonization and stalling during radiofrequency ablation and electrosurgery
Radiofrequency (RF) thermal therapies, including RF ablation and electrosurgery, function by delivering alternating currents in the 100 kHz-1 MHz range to biological tissues. These currents generate electric fields that drive ionic oscillations in intracellular and extracellular fluids, producing …
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The Potential for Ultrasonic Image-Guided Therapy Using a Diagnostic System
… to many surgical procedures. Ultrasonic thermal therapies can also be used to release thermally sensitive liposomes encapsulating chemotherapeutic drugs. In the brain, the permeability of the blood-brain barrier to drugs, antibodies, and gene transfer can be increased with a mechanical …
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3D Temperature Imaging Using Ultrasonic Backscatter Energy during Non-Uniform Tissue Heating
… and spatial resolution on estimation errors, thermal modeling was done for non-uniform heating using finite element methods. Temperature estimation was tested during non-uniform heating in both gelatin and tissue phantoms. Specimens were heated from a central source so that the spatial …
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Non-invasive in vivo ultrasound temperature estimation
New emerging technologies in thermal therapy require precise monitoring and control of the delivered thermal dose in a variety of situations. The therapeutic temperature changes in target tissues range from few degrees for releasing chemotherapy drugs encapsulated in the thermosensitive liposomes …