Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Therapeutic investigation"”.
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A functional and therapeutic investigation of ciliopathy proteins and ciliopathies
… ciliopathy proteins and identify candidates for therapeutic application. The ciliopathies form a class of genetic diseases whose aetiology lies in the primary cilium. Over 30 genes have been identified as mutant in ciliopathies and their proteins localise at the primary cilium. When mutated they …
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In Vitro Equine Flexor Tendonitis: New Model Development and Therapeutic Investigation
… regenerative medicine to improve tissue healing. Investigations of new treatments are made difficult by the lack of reliable in vitro models that allow for accurate comparison of treatment protocols. New techniques are often implemented into the clinical setting prior to thorough investigation for …
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Pathological and therapeutic investigations in tuberculosis: PART I PATHOLOGICAL INVESTIGATION - an investigation into hypersensitivity in tuberculosis as illustrated by the response of the skin, and of the leucocytes of the blood to tubérculin; PART II THERAPEUTIC INVESTIGATION - a clinical evaluation of the use of para-aminosalicylic acid in the treatment of pulmonary tuberculosis.
PART I PATHOLOGICAL INVESTIGATION - (a) The disintegration of the neutrophil polymorphnuclear cells of the blood of a tuberculous individual is accelerated (when clotting is prevented.) in vitro by the addition of tuberculin.
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Investigation of Drp1 inhibition as potential therapy in pesticide-based models of Parkinson's disease
… model for the exploration of potential therapeutic agents. Paraquat experiments in Oct3-/- mice demonstrated that pharmacological inhibition of Drp1 with mdivi-1 was protective against the paraquat-induced neuropathology, however investigation of genetic Drp1 modulation in the global …
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The characterisation of the cell surface of Staphylococcus aureus in the search for new therapeutic targets
… available, the development of an alternative therapeutic would not only relieve morbidities, mortalities, and the associated economic burden, but also reduce the selective pressures that drive antibiotic resistance. To better understand how S. aureus interacts with the human host and presents …
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Using immune cells to combat obesity: adipose eosinophils as mediators of metabolic homeostasis
… allowed us to generate a list of candidates for therapeutic investigation, with potential for future clinical discovery. Together, these results have cemented the role of adipose eosinophils as homeostatic cells with important roles in the maintenance of metabolic health, which could be exploited …
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Takotsubo Syndrome: Precipitants, Clinical Course and Emerging Treatments
… clinical trial represents the first prospective therapeutic investigation in TTS, additional future studies are also needed to develop interventions to prevent the occurrence and recurrence of TTS.