Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Therapeutic Systems"”.
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Thermally-responsive interpenetrating polymer network nanoparticles as intelligent therapeutic systems
Thermally-responsive interpenetrating polymer network (IPN) nanoparticles, composed of polyacrylamide, poly(acrylic acid), poly(methacrylic acid), poly(2-ethylacrylic acid), and poly(2-propylacrylic acid), were synthesized using a sequential inverse emulsion polymerization technique. These …
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Preparation and analysis of novel tumour-targeted delivery systems for prostate cancer therapy
… system able to improve the delivery of the therapeutic gene to cancer cells, in a safe and targeted way. We demonstrated that new tumour-targeted therapeutic systems recognizing receptors specifically overexpressed on prostate tumours, were able to improve the in vitro therapeutic efficacy …
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Preparation and evaluation of tumour-targeted delivery systems for tocotrienol
… properties on cancer cells. However, its therapeutic potential was hampered by the limited ability to reach tumours specifically after intravenous administration. In this study, we aim to develop a formulation of tocotrienol that could be specifically delivered to tumours upon intravenous …
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Preparation of a self-contained NADH co-factor recycling particle system
… and co-factors have been developed. These systems are of interest as they offer the advantages of recycling the enzymes together with the co-factor, thereby enabling re-use. The immobilisation of enzymes also provides a platform for improving their stability, activity, specificity and …
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EEG-Based Control of Working Memory Maintenance Using Closed-Loop Binaural Stimulation
… brain is a highly complex network of nonlinear systems with internal dynamic states that are not easily quantified. As a result, it is essential to understand the properties of the connectivity network linking disparate parts of the brain used in complex cognitive processes, such as working …
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Encoding and Decoding of Pain Relief in the Human Brain
… to anatomically dissociate underlying neural systems. Experiment 2 focused on relief learning of terminating a tonic pain stimulus, in which the priority for relief-seeking is in conflict with the general suppression of cognition and attention. I showed that associability during active …
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Design and Synthesis of Stimuli-Responsive Polymers with Programmable Cleavability
… bottlebrush polymers as nanocarriers for therapeutics, and provides a detailed literature analysis of the synthetic and architectural developments that have been reported for these constructs, as well as outlooks for the future. The second chapter reports the first synthesis of …
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Development of tumour imaging and therapy strategies utilising unengineered bacteria
… for the delivery of nucleic acid, protein or therapeutic payloads to tumour sites and present researchers with a highly targeted and safe vehicle for tumour imaging and cancer therapy. This work aimed to utilise bacteria to activate imaging probes or prodrugs specifically within target tissue …
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Charakterisierung der Mikrostruktur und der Permeationseigenschaften von Polysiloxan-Netzwerken
Ziel dieser Arbeit war es, die Permeationseigenschaften von Polysiloxan-Membranen im Hinblick auf ihre definierte Mikrostruktur näher zu analysieren. Es konnte gezeigt werden, dass die Mikrostruktur der Membranen einen statistisch signifikanten Einfluss auf die Permeationsgeschwindigkeit der …