Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Tg2576 mouse model"”.
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PPARγ-pERK interaction restores memory consolidation in an Alzheimer’s disease model
… feature of Alzheimer’s disease (AD) and AD mouse models. We and others have previously reported the peroxisome-proliferator activated receptor gamma (PPARγ) agonist rosiglitazone improves hippocampus-dependent cognitive deficits in some AD patients and ameliorates deficits in the Tg2576 …
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Microbial Metabolite Regulation of Microglial AHR Signaling in Alzheimer’s Disease
… accelerates AD progression. </p> <p>Methods: The Tg2576 mouse model was used for this study, in which mice develop amyloid plaques and cognitive deficits at 12 months of age. Mice were aged to 9 and 15 months to study the progression of AD from the pre-symptomatic and post-symptomatic time points. …