Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"Tfr"”.
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TFR Cells Suppress Gut Commensal-Specific IgA Via IL-10
… IgA. Concurrently, T follicular regulatory (TFR) cells, derived from regulatory T cells (Tregs), also regulate this process. TFR cells suppress or enhance Ab responses depending on the context, but their role in gut IgA responses remains unclear. Based on our preliminary data, we hypothesized …
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Follicular Regulatory T cell migration and differentiation
… GC response requires Follicular regulatory T (Tfr) cells, a subset of Foxp3+ Treg cells located within germinal centres. Tfr cells were first characterised in detail in 2011 and because of this relatively little is known about the exact role of Tfr cells within the GC, and the mechanism/s …
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Characterization of Allergen-Specific Immunoglubulin E Development in a Food Allergy Model and Its Regulation by T Follicular Helper and T Follicular Regulatory Cells
… cells (TFH) and T follicular regulatorycells (TFR) in the germinal center (GC). We aimed to understandthe regulation of IgEin the GC by TFH and TFR cellsusinga mouse food allergy model. We found that the dosage and timingof allergen delivery into thegut is criticalfor allergen-specific IgE …
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Regulation of Autoimmune Germinal Center Reaction By Tfh Cells and Application of Tfr-Like Cells For The Treatment of Autoimmune B Cell Responses
… cells are termed as follicular regulatory T (Tfr) cells. Due to their ability to specifically suppress Tfh cell and GC B cell responses, use of Tfr cells may be a promising target-specific therapy for the treatment of autoantibody-mediated autoimmune diseases. To evaluate the role of Tfr cells …
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The United Nations Fund For Population Activities: Changing The Direction Of The Total Fertility Rate In Developing Nations
… factors affecting the Total Fertility Rate (TFR) in six (6) states: Burkina Faso, Mexico, Morocco, Nepal, the Philippines, and Uganda. The present research, however, provides a broader assessment of the TFR and the potential causes of its decline by examining countries across nine (9) regions …
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Study of a Transferrin Receptor Brain Shuttle for the Delivery of Nanobodies Against GABAA Receptors
… at the BBB, such as transferrin receptor (TfR), hijacking endogenous trafficking systems to shuttle conjugated therapeutic cargo from the blood circulation into the brain parenchyma. Such systems could be utilised to improve the delivery of novel immunogenically-raised nanobodies (Nbs), …
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Structure of the trypanosome transferrin receptor and insights into ligand binding and therapeutic strategies
… the expression of a transferrin receptor (TfR), which does not share homology with the host TfR. Multiple diverse copies of the TfR are present in the trypanosome genome but only one is expressed at a time. Several hypotheses revolve around the evolutionary advantage of multiplication and …
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Bragg reflector thin-film resonators for miniature PCS bandpass filters
Thin-Film Resonator (TFR) based bandpass filters are an economically attractive alternative to current dielectric filters. TFR based filters are orders of magnitude smaller and can potentially be manufactured on-chip, thereby allowing VLSI integration of bandpass filters into a RF portable radio …
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Regulation of the germinal center reaction by T helper cells and T regulatory cells
… controlled by regulatory follicular T helper (TFR) cells, a subset of Treg cells. To study the mechanism of how TFR cells regulate the GC reaction, we generated mice specifically lacking TFR cells by specifically deleting Bcl6 in Treg cells. Following immunization, these "Bcl6FC" mice developed …
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Applications and Extensions of Quadratic Signal Representations
… on developing nonnegative, high-resolution TFRs that correspond with intuitive notions of energy distribution. These so-called consistent TFRs are developed by requiring the desired representation to be consistent with a set of spectrogram-based energy measurements. The desired …
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Food Habits, Growth, Conversion Efficiency and Response to Prey Odors of the Copperhead, Agkistrodon Contortrix
… conversion efficiency, and tongue flick rate (TFR) during exposure to food odors were investigated during this study. Sixty-one adult copperheads were examined for prey remains and yielded 31 prey items of which 50% were small mammals. Captive neonates were observed to feed only on small …
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The Development of a Drug Delivery System Using Brain Endothelial Non-Antibody Binding Domains as Transport Carriers
… BCEC receptors such as transferrin receptor (TfR) have been proposed as exploitable targets for therapeutic payload transport into the CNS, and have been successfully targeted using monoclonal antibodies to deliver therapeutic molecules into the brains of rodents and non-human primates via …
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Assessment of subnational level birth registration data in South Africa
… of births and estimating total fertility rate (TFR). The study further analyses the spatial relationships between respective districts to each other based on levels of birth completeness and total fertility rate. The Geographical Information Systems (GIS) technique of the Global Moran's Index …
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Lower leg and foot contributions to turnout in pre-professional female dancers: A clinical and kinematic analysis
… via additional external tibiofemoral rotation (TFR) and foot pronation. Yet knowledge of these compensatory mechanisms is based on biomechanical theories and clinical observations rather than quantitative clinical assessments or 3D motion analysis. The principal aim of this research was to …
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A T- és B-limfocita alpopulációk eloszlásának vizsgálata endometriózisos betegekben
… a follikuláris regulatorikus T-limfociták (Tfr), valamint a különböző érett és naiv B-limfocita populációk arányát. Az endometriózisos pácienseknél a Th2-szerű Tfh sejtek aránya szignifikánsan csökkent (p=0,0415), a Th1/17-szerű Tfh sejtek aránya nőtt (p=0,0061) a kontroll csoporthoz …
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Is Playerload related to fatigue following different types of repeated maximal sprint exercises in recreationally active young men?
… (VA) and the torque-frequency relationship (TFR) were measured in the hamstring muscle group using electrical stimulation at the same time points. Blood samples were drawn from the antecubital vein pre, post and post 48 hr completion of the protocols Results: PL (126.8 ± 13.8 vs. 107.6 ± 12.7 …
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The determinants of contraceptive use in Zambia
… per cent in 2007; while total fertility rate (TFR) fluctuated between 6.5 and 6.2. The study uses three Zambian Demographic and Health Survey (DHS) data sets for 1996, 2001-2 and 2007 and applies multivariate logistic regression techniques to identify factors affecting the use and choice of …
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Multi-modal imaging of herpesvirus infection
… roles of TGN46- and transferrin receptor (TfR)-positive vesicles in the cytoplasmic envelopment of HSV-1 capsids. Striking changes occur to the morphology of mitochondria and the organisation of cytoplasmic vesicles and lipid droplets during HSV-1 infection. Comparative tomographic analysis …
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REPSA Directed Assessment of Native Cleavage Resistance of DNA to Type IIS Restriction Endonucleases and Modification of REPSA for High Temperature Application
… thermophilic organism. We used a TetR Family (TFR) transcription factor SbtR as the model protein for optimization of HT-REPSA protocols, as data had previously been obtained regarding SbtR physical characteristics and DNA-binding properties. REPSA was conducted until a cleavage resistant …
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Socio- Economic differentials in fertility in Zimbabwe from 1980 to 2005
… and fertility based on the total fertility (TFR), CPFRs and projected PPRs estimates. Further analysis of the net effects of economic status and education using multivariate logistic regressions suggests the odds of having a child (not having a child) decreases (increases) with economic …
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