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Showing 1 to 1 of 1 for “"Tetrahydropalmatin"”.
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Asymmetric synthesis of trisubstituted isoindolines and tetrahydropalmatine via tandem 1,2-addition-cyclisation
… to the total synthesis of both enantiomers of tetrahydropalmatine. Reaction of 2,3-dimethoxy-6-methyl benzamide and 3,4-dimethoxybenzaldehyde SAMP- or RAMP-hydrazone gave the dihydroisoquinolones in high diastereomeric purity (de = 96%) and reasonable yield (54-55%) taking into account the …