Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 79 for “"Tetrahydrocannabinol"”.
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Single Liquid-Liquid Extraction of Delta-9-Tetrahydrocannabinol and 11-<i>Nor</i>-Carboxy-Delta-9-Tetrahydrocannabinol at an Acidic pH
<p>Because of the high occurrence of marijuana usage in the workplace and in driving under the influence cases, it is important to test for both delta-9-THC and delta-9-THCA in order to determine current and recent usage. The laboratory preparation and analysis of delta-9-THC and delta-9-THCA in …
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The combined effects of cannabidiol and delta-9-tetrahydrocannabinol
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Comparison of Extraction Techniques for Δ-9-Tetrahydrocannabinol from Urine
<p>With the increasing use of marijuana, efficient methods to extract and detect Δ-9-THC in urine samples and relate the concentrations found to time is a necessity so that impairment can be determined. Δ-9-THC is conjugated to glucuronic acid in urine and must be freed before the compound can be …
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The use of tetrahydrocannabinol (marinol) in cancer patients undergoing chemotherapy
… effect of Marinol, which contains the antiemetic tetrahydrocannabinol (THC), was evaluated in five cancer patients undergoing chemotherapy. Subjects rated their nausea and vomiting, food intake, appetite and mood status three times daily. Drug therapy (THC) or no drug was administered for an …
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Mucoadhesive buccal tablets for the delivery of nicotine and Delta9-tetrahydrocannabinol.
… the use of cannabinoids, particularly Delta9 - tetrahydrocannabinol (Delta9-THC), in a number of legitimate medical conditions. Buccal tablets containing Delta9-THC were prepared in an attempt to provide a standardised dose of Delta9-THC at controlled rates via the buccal mucosa. Tablets were …
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Characterizing the Developmental and Reproductive Toxicities of Cannabidiol and Δ9-Tetrahydrocannabinol
… without including low concentrations of Δ9-tetrahydrocannabinol (THC). The goal of this project is to characterize the relative morphological, behavioral, reproductive, and multigenerational toxicities following a developmental F0 exposure to 0.024–5 mg/L (0.08–16 µM) THC or 0.006–1.2 mg/L …
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The influence of cannabidiol on the effects of delta-9-tetrahydrocannabinol
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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The Developmental and Behavioral Effects of Δ9-Tetrahydrocannabinol on a Spastic Mutant
<p>Hyperekplexia is a neurological disorder affecting infants and can be characterized by excessive startle reactions in response to unexpected stimuli. This disease can be modeled in zebrafish in the bandoneon (beo) mutant, where the <em>glrbb</em>mutation results in glycine receptor (GLYR) loss …
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Impact of Oxytocin and Tetrahydrocannabinol on signs of fear in the rat
<p>BACKGROUND: Oxytocin (OXT) has been used as a post-treatment for post-traumatic stress disorder (PTSD). Previous research suggests that pre-treatment of intranasal OXT attenuates signs of fear in rats; however, the impact of intraperitoneal (i.p) OXT pre-treatment on signs of fear in rats is …
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Effects of alcohol and ∆9-tetrahydrocannabinol on energy balance and cognitive behaviors
… to overweight and obesity is debatable. ∆9-tetrahydrocannabinol (THC), the main psychoactive constitute of marijuana, mainly activates cannabinoid subtype 1 and 2 receptors (CB1R and CB2R) to modulate many behavioral and metabolic processes, including feeding and glucose homeostasis. For …
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Effects of Δ9-Tetrahydrocannabinol on Neural Reward Anticipation Among Young Adult Cannabis Users
… and chronicity of use, while acute delta-9-tetrahydrocannabinol (Δ⁹-THC) intoxication may further modulate these effects, though findings are mixed. The present study explored (1) the relationship between problematic cannabis use and neural reward anticipation, (2) the effects of acute …
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Genetic Variation and Sex Mediate Differential Responses to ∆-9-tetrahydrocannabinol among Inbred Mice
… and later isolated. In the 1970’s, ∆9-tetrahydrocannabinol (THC) was isolated and recognized as the major constituent responsible for the psychoactive and intoxicating effects associated with consumption of cannabis. This opened the door for intensive research in the field that lead to …
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Preformulation Characterization And Formulation Development of Δ9-Tetrahydrocannabinol Prodrugs For Potential Treatment Of Glacuoma
… could be linked to this observation. Delta-9-Tetrahydrocannabinol (THC) was one of the ingredients identified. However, four decades and numerous research efforts since the first observation, it has still not been concluded whether THC is effective in the treatment of glaucoma or not. Current …
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The Effects of Δ9-tetrahydrocannabinol (THC) on development and hyperekplexia in embryonic zebrafish model
… produced by the cannabis plant, Δ<sup>9</sup> – tetrahydrocannabinol (THC) has been shown to the most efficacious phytocannabinoid in neurological disorders. THC has been shown in numerous previous studies to be effective at treating spasticity caused by multiple sclerosis and spinal cord injury, …
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Associations between number of standard doses of tetrahydrocannabinol, cannabis use motives and cannabis-related negative consequences
… the establishment of a standard unit of Tetrahydrocannabinol (THC) to be used in research. To address this notice, the current study examined if associations between cannabis use and cannabis related consequences and cannabis use motives would differ when using standard dose as a measure …
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The Effects of Early-Life Lead Exposure on Adult Delta9-Tetrahydrocannabinol Sensitivity, Self-administration, and Tolerance
… cannabis (main psychoactive component delta-9-tetrahydrocannabinol) have been shifting, and many American states have legalized the recreational use of cannabis. It is also the 3rd most widely used drug of abuse in the US, and rates of cannabis use disorder are on the rise. This thesis sets out …
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