Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 26 for “"Tetracyclines"”.
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Tetracyclines In Swine Waste
<p>Antibiotics are added to animal feeds as prophylactic agents and to encourage weight gain in livestock. However, there is concern that the widespread use of antibiotics in animal agriculture encourages for the selection of resistance genes and has contributed to the rise of multiply antibiotic …
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Transition metal complexes of tetracyclines
… to observe their complexing properties with the tetracyclines. Four metals were found to form sufficiently strong complexes with the tetracyclines to provide a basis for a rapid, reliable method of assaying the potency of the tetracycline products used in medicine today. Microbiological methods …
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The role of soil clays and clay-humic complexes in processes controlling colloidal stability and the sorption and degradation of tetracyclines
… their interactions on sorption and desorption of tetracyclines. Tetracyclines are important in human medicine and are also used extensively in livestock production. Chlortetracycline and tetracycline are routinely used for growth promoting and therapeutic purposes in livestock production. To …
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Cisplatin cytotoxicity associated with tetracycline resistance determinants in Escherichia coli
Tetracyclines, a broad-spectrum class of antibiotics, were discovered in the late 1940s, and became widely used because of their important advantages: they are inexpensive, safe, demonstrate good oral absorption, and are active against a broad range of bacterial pathogens. Unfortunately, as with …
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Evaluation of Macrolide-Lincosamide-Streptogramin B Antimicrobial Resistance at Swine Farms
… targeting fecal streptococci. Furthermore, tetracyclines were detected in the swine waste samples, suggesting that selective pressure from tetracyclines may result in MLSB resistance. Clostridium spp. were identified as a dominant population contributing to the high level of MLSB resistance …
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Design of a Tetracycline Operon Inducible System for the Control of Vaccinia Virus Replication: Implications for Vaccine Development
… be regulated through the addition or removal of tetracyclines. Seven VACV genes were tested in an attempt to control viral replication. For each gene a different recombinant was generated in which the essential gene was placed under the control of <em>tet </em>operon elements. Of the seven VACV …
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Tetracycline-7-boronic acid
… high-energy alpha radiation. The fact that the tetracyclines are not retained by normal tissue should remove the danger of destruction of this tissue.
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Optimizing a protein-RNA aptamer gene regulatory system using an engineered peptide library
… 5-1.2 to modulate gene expression. With no tetracyclines present, TetR preferentially binds to aptamer 5-1.2 in the mRNA of a gene of interest with low nanomolar affinity and represses translation. Tetracyclines such as aTc induce a conformation change in TetR, prevent TetR binding to …
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The effects and fate of selected veterinary antibiotics in two Missouri anaerobic swine lagoons
… that the sorption trends varied according to: tetracyclines> tylosin A>> lincomycin> sulfonamides"--Abstract, page iv.</p>
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Structure-Based Drug Design Against a Biosecurity Pathogen
… revealing two new mechanisms of action for tetracyclines against the large subunit. These explain the potency of doxycycline against C. burnetii and, for E. coli, reveal a novel inactive conformation of the ribosome, potentially explaining observed bactericidal tetracycline behaviour. Both …
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Excretion of Antibiotic Resistance Genes by Dairy Calves
… from feces, and ARG corresponding to the tetracyclines (tetC, tetG, tetO, tetW, and tetX), macrolides (ermB, ermF), and sulfonamides (sul1, sul2) classes of antibiotics along with the class I integron gene, intI1, were measured by quantitative polymerase chain reaction (qPCR). No tetC or …
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Phenotypic and molecular characterization of coagulase negative staphylococci from pigs and humans in Lusaka province, Zambia.
… multidrug resistance at 60.7% to beta-lactams, tetracyclines, phenicols, sulfonamides, lincosamides and aminoglycosides. While, Methicillin Resistant-CoNS were prevalent when tested using phenotypic methods, none of the MR-CoNS tested positive for the mecA gene using PCR, suggesting other …
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Phenotypic and molecular characterization of coagulase negative staphylococci from pigs and humans in Lusaka province, Zambia.
… multidrug resistance at 60.7% to beta-lactams, tetracyclines, phenicols, sulfonamides, lincosamides and aminoglycosides. While, Methicillin Resistant-CoNS were prevalent when tested using phenotypic methods, none of the MR-CoNS tested positive for the mecA gene using PCR, suggesting other …
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Analysis of Minocycline as a Radioprotectant
… impairment. The literature suggests that tetracyclines can be radioprotectors of the hematopoietic system with potential utility in radiation emergencies and anticancer radiotherapy. Minocycline, a semisynthetic tetracycline derivative, has anti-inflammatory, free radical scavenging, …
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ST-1 VISA/DAP-R CA-MRSA INTEGRATED OMICS: A FIRST REPORT OF HYPER-VIRULENCE AND MULTI-DRUG RESISTANT SUPERBUG
… in aminoglycosides, β-lactams, macrolides and tetracyclines resistance, reflecting a multi-drug resistant behaviour. While the Virulome underlined the presence of adhesins, capsular polysaccharides, clumping factors, endotoxins, haemolysins, and leukotoxins including genes encoding the …
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Characterization of Atypical Hemolytic Ornithobacterium rhinotracheale Isolates and Comparison with the Normal Non-Hemolytic Phenotype
… in growth characteristics and resistance to tetracyclines were also noted. No differences in proteins, biochemical characteristics or 16S rRNA sequences were found, the latter serving as confirmation that the isolates were both ORT. Embryo inoculation was used to assess virulence. No …
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Epidemiology of antimicrobial resistance at the livestock-human interface in an urban environment: a One Health approach
… resistance to sulfonamides, aminoglycosides, tetracyclines, and β-lactams respectively – the most commonly found phenotypes. Highest carriage of AMR genes and phenotypes was observed in humans, pigs and poultry compared to goats, rabbits and bovines. Secondly, I demonstrated that the presence …
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Characterization Of Antimicrobial-Resistant staphylococcus Spp. In Food Animals And Retail Meat
… 96% of the isolates. Resistance to macrolides, tetracyclines, and Q/D, in addition to Β-lactam resistance was observed with 54% isolates classified as multi-drug resistant. <i>tet</i>(M) was conjugatively transferable from 10 tetracycline-resistant CoNS to other commensals like <i>Enterococcus …
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Antibiotikų skyrimo ypatumai suaugusiems, sergantiems kvėpavimo takų infekcijomis, pirminės sveikatos priežiūros įstaigose Lietuvoje /
… RTIs were broad spectrum penicillins (62,3%), tetracyclines (11,3%), macrolides (10,0%). The structure of prescribed antibiotics in private centers and polyclinics, between males, females and age groups was similar. Diagnostic tests were more frequently performed in polyclinics (70,3% from all …
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Genetic and phenotypic diversity of bloodstream associated Staphylococcus epidermidis isolates obtained from private and public hospitals in South Africa
… tetK and msrA genes conferring resistance to tetracyclines, aminoglycosides and macrolides. The following virulence genes were prevalent among the private hospital isolates; EMBP [97.9% (96/98)], agrA, and aae [all at 95.9% (94/98)]. Among public hospitals isolates, the agrA [93.7% (59/63)], …
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