Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 131 for “"Tet"”.
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An Effective Transcutaneous Energy Transfer (TET) System for Artificial Hearts
… and LVADs. Transcutaneous Energy Transfer (TET) systems use magnetic fields to transfer power across the skin without direct electrical connectivity. This offers the prospect of lifetime operation and overcomes the infection risk associated with wires passing through the skin. The major …
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Gene Therapy Using Tet-Repressor System to Modulate Prostate Tumor Microenvironment
… model in this study we took advantage of the tetracycline inducible expression system that enabled us to control the expression of the chemokines and cytokines during the course of study. We showed that expression of SLC in the TRAMP TME inhibited tumor growth, decreased metastasis and …
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A Tet-repressible regulation system in mycobacteria for application to vaccine design
Includes abstract. Includes bibliographical references (leaves 116-123).
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Nucleobase, Nucleoside, And Neighboring Nucleotides: Intrinsic Preferences For Tet Enzyme-Mediated Oxidation Of 5-Methylcytosine
The Ten-eleven-translocation (TET) family of enzymes can oxidize the fifth base of DNA, 5-methylcytosine (mC) sequentially, to 5-hydroxymethylcytosine (hmC), 5-formylcytosine (fC), and 5-carboxycytosine (caC). The biochemical preference of TET enzymes for these substrates, in the canonical cytosine …
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The Role of TET Proteins in the Epigenetic Regulation of Neural Gene Expression and Behavior
… in gene-targeting technology. Recently, the Tet gene family was discovered and implicated in epigenetic modification of DNA methylation by converting 5-methylcytosine to 5-hydroxymethylcytosine (5hmC). 5hmC and its catalysts, the TET proteins, are highly abundant in the postnatal brain but …
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News Media Coverage of the Attack on the American Embassy in Saigon During the 1968 Tet Offensive
The 1968 Tet offensive is referred to as the turning point in the Vietnam War. Of the many battles of Tet, the attack on the American Embassy in Saigon stands out. It is neither the battle's size nor its casualties that makes it important. The significance of the embassy attack lay in the way it …
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Maintaining Proper Levels of DNA Methylation Marks Through the TET Family is Critical for Normal Embryo Development in Pigs
… embryo development. Ten-eleven translocation (TET) methylcytosine dioxygenases are implicated in DNA demethylation by catalyzing the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). The three members of TET protein family, TET1, TET2, and TET3, are highly expressed in …
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Different Genetic Ways for Conditional Gene Regulation in the Mouse Brain
… gene expression system controlled by the tetracyclineresponsive trans-activator (tTA) in transgenic mice is an important and well characterized genetic tool. In my studies I investigated the function of the Tetregulated genes in the brain when inserted into the chromosome and when applied …
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Antibiotic resistance gene abundance in feces of calves fed pirlimycin-dosed whole milk
… copies/copies of 16S rRNA genes) of erm(B), tet(O), tet(W) and 16S rRNA genes. Data was analyzed using PROC GLIMMIX in SAS. Abundance of 16S rRNA genes, tet(O) and tet(W) were not different between control and pirlimycin-fed calves nor were the relative abundance of tet(O) (mean = 0.050 …
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ELUCIDATION OF MECHANISMS GENERATING 5-HYDROXYMETHYLCYTOSINE (5hmC) IN MAMMALIAN MITOCHONDRIA
… gene expression, and development. Recently, the Tet family of methylcytosine dioxygenases(Tet1, Tet2 and Tet3) was found to catalyze the oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), an intermediate in the pathway of DNA demethylation. Tet enzymes catalyze this …
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Spatial and temporal regulation of IL4Rα expression
… This has been achieved by using the established Tet System (Goosen and Bujard, 1992) where the crossing of two complementary transgenic mouse lines enable the generation of the final double transgenic model. The first line expresses the transactivator, tTA, from the Tet-Off expression cassette …
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Cytokine gene transfer by adenoviral vectors as a novel therapeutic option for hepatitis B virus infection
… AdmIFNb) and the second using a bidirectional tetracycline (tet)-regulated promoter(Pbi-1) (Adbiluc vectors) to locally express mouse interferon (mIFN) a, b and g. In mouse hepatocyte cultures, a 5- to 10-fold decrease of intracellular HBV DNA was observed following infection with AdmIFNb or …
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Automatic recognition of Persian musical modes in audio musical signals
… for training; down sampling; tone resolution (12-TET, 24-TET, 48-TET and 53-TET); the effect of using overlapping or nonoverlapping frames; and silence and high-energy suppression in pre-processing. The santur (hammered string instrument), which is extensively used in the musical database samples, …
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Der LC-1-Locus im Mausgenom: ein geeigneter Ort für die stringente Regulation von "Transgenen" via Tetrazyklin ?
… vor allem das in unserem Labor entwickelte Tet-System durchgesetzt, das auf den Kontrollelementen des Tetrazyklin-Resistenzoperons des Tn10 aus E. coli basiert und die Transkription von Genen mittels Doxyzyklin (Dox) zu kontrollieren erlaubt. Ein zentrales Element in diesem System ist Ptet, …
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Experimentelle Untersuchungen zum retroviralen Gentransfer in primäre Chondrozyten des Kaninchens
… ein weiteres Ziel die Entwicklung retroviraler Tet-On-Vektoren. Es wurden konstitutiv exprimierende retrovirale Vektoren und Tet-On-Vektoren kloniert und Retroviren mit unterschiedlichen Infektionsspektren generiert. Effizienz und Stabilität des Gentransfers wurden ohne weitere …
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Tyrosine Phosphorylation of Villin: Effects on Actin Dynamics, Cell Morphology and Cell Migration
… of villin in doxycyline-regulated HeLa Tet-off and MDCK Tet-off cells enhanced cell migration. We further demonstrate that tyrosine phosphorylation of villin by c-src is required for villin-induced cell migration. Previously, we identified four tyrosine phosphorylation sites in the …
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Controlling Triplet Excitons in Organic Semiconductors with Lanthanide-Doped Nanoparticles
… (TAS), we show triplet energy transfer (TET) to be governed by a concerted Dexter-type process. Contrary to previous beliefs, we find near-unity TET efficiencies that are independent of distance over the range of OSC–LnNP separations investigated. We show that close coupling between the …
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