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Showing 1 to 1 of 1 for “"Testosterone depletion"”.
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Expression of perforin and granzyme variants in adult rat testes after ethylene dimethane sulfonate (EDS)-induced testosterone depletion
Testosterone is essential for regulation of spermatogenesis and testosterone withdrawal results in germ cell apoptosis. However, the mechanism for germ cell apoptosis is unknown. In testes, mature Leydig cells produce testosterone. Using ethane dimethane sulfonate (EDS), a Leydig cell-specific …