Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 28 for “"Testicular Cancer"”.
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Breast and Testicular Cancer Screening Activities of Nurse Practitioners
… trends in health care, two self care activities, testicular self-examination (TSE), breast self-examination (BSE), the clinical examination of each and mammography have been encouraged in the detection of specific cancers. Nurse practitioners, who by virtue of their nursing background, have …
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Testicular cancer – response adapted treatment, prognostic markers and survivorship issues
In the US and most European countries, testicular cancer is the most common malignancy in young men aged 20-40 years. Since the introduction of cisplatin-based treatment in the 1970s, more than 95% of the patients are cured. The increasing incidence of testicular cancer and high survival rates, has …
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Toward a mechanistic understanding of poly- and perfluoroalkyl substances and testicular cancer
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-10-19 without embargo terms
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Testicular cancer; gonadal, sexual and psychological aspects of the disease and its treatment.
The survival rates among testicular germ cell cancer (TGCC) patients have dramatically increased and more than 95 % are cured. The question of quality of life of the survivors is, therefore, important. The TGCC treatment, and thereby its side-effects may vary. A contributing factor to this …
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The psychological implications of surviving testicular cancer : impact on body image, sexuality and masculinity
INTRODUCTION: Men's health generally and testicular cancer in particular are neglected areas of research. This particular malignancy is the most common among young men in the western world (Champion, 1996), and its prevalence is on the increase, however, so too are cure rates. As a consequence …
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Increased Testicular Cancer Education and Self-Examinations among Males at Spectrum Healthcare’s Mingus Mountain Clinic
… of this DNP project was to assess current testicular cancer and testicular self-examination knowledge, provide education through informational handouts and evaluate learning to increase awareness of risk factors and signs/symptoms associated with testicular cancer (TC). Methods: A …
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Psychosocial Adjustment to Cancer in Younger Adults with Hodgkin Lymphoma or Testicular Cancer: Transitions to Survivorship
Background: Cancer is an unexpected diagnosis in young adulthood, which can disrupt normal developmental milestones. Testicular cancer and Hodgkin lymphoma typically affect young adults, however relatively few studies have explored the psychosocial impact of these cancers. This thesis aimed to …
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The Relationship Between Health Belief Model Constructs and Factors Influencing Cancer Self-Examinations in College Students
… study is to explore college students' breast and testicular cancer self-examination beliefs and practices using constructs of the Health Belief Model. Over a 1.6 million Americans are diagnosed each year with cancer. With that, over 200,000 women will be diagnosed with breast cancer while nearly …
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Reproductive health effects due to pesticide exposure amongst boys in the rural Western Cape, South Africa
… abnormalities are reproductive organ defects, cancers and declining fertility. Cryptorchidism, hypospadias, testicular cancer and poor sperm quality (testicular dysgenesis syndrome) have also been reported to be associated with these endocrine-disrupting chemicals. This study therefore aims to …
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Molecular and cellular expression of novel genes associated with breast cancer
An improved and individualised breast cancer care can be pursued with the use of tumour markers that are associated with risk assessment, diagnosis, prognosis, prediction of treatment outcome, monitoring of the disease and development of novel therapies. As such, this study proposed to characterise …
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Photo-cross-linking and identification of nuclear proteins that bind to DNA containing a site-specific adduct of cis-[Pt(NH₃)(N-6-aminohexyl)-4-benzophenonamide)CI₂]
… or cisplatin, is the most successful cancer drug ever discovered. It has been used for over 30 years in the treatment of several types of malignancies, with the highest success rates in testicular cancer patients. Despite the triumphs of this drug, the exact mechanisms of cell-killing …
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Metabolic and mechanistic exploration of a novel programmable genotoxicant against prostate cancer
… its success as a chemotherapeutic agent against testicular cancer. The new compounds are designed to utilize proteins such as steroid receptors that are abnormally expressed in cancers to enhance toxicity and specificity. The synthetic phase of this project successfully produced a compound, 11P, …
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Reproductive function in young Swedish men - Time trend, prenatal and adult exposure to smoking and phthalates
… has been postulated. During this period, testicular cancer has increased several-fold. Environmental and lifestyle-related factors have been proposed as explanations for a possible negative trend in male reproductive function. One important lifestyle factor is smoking. However, smoking …
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Molecular mechanism of interactions between estrogen receptor and estrogen receptor selective genotoxins
Although one million new breast cancer cases arise each year worldwide, therapies to treat the disease are limited. Conventional treatments including the chemotherapeutic agent, Tamoxifen, have had only limited success, often showing uncomfortable side effects. Our group has proposed a new scheme …
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The impact of genetic, environmental and life-style factors on male reproductive function
… than in Denmark. In parallel, the incidence of testicular cancer (TC) and of congenital malformations of male genital organs is significantly higher in Denmark as compared to Finland. Previous studies have shown an association between decreased sperm quality and risk of TC. Recently, it was …
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The androgen receptor independent mechanism of toxicity of the novel anti-tumor agent 11[beta]-dichloro
… by the toxicity mechanism of cisplatin in testicular cancer, a series of bi-functional genotoxicants has been designed that supplement their DNA damaging properties with the ability to interact with tumor specific proteins. One such compound, 11[beta] -dichloro links an aniline mustard …
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Vasculogenic mimicry in bladder cancer and its association with cancer stem cells and human chorionic gonadotropin-beta
Bladder cancer is the 11th most common cancer in the United Kingdom and it is the fourth most common cancer in men. It has been found that some cancerous tumours acquire resistance to antiangiogenic therapy due to different angiogenic “escape “ pathways that allow tumours to restore their growth …
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A study to understand the experiences of adolescents and young adults living with cancer in a northern cape public health setting
… of adolescents and young adults (AYAs) with cancer in low- and middle-income countries are under-researched. This limits evidencebased information regarding their experiences related to palliative care and quality healthcare services, resulting in a neglect in planning services for this …
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Understanding and improving the anticancer activity of cisplatin
… (cisplatin), one of the most effective anticancer drugs. Since its serendipitous discovery in 1970, cisplatin has served to help cure testicular cancer and treat a variety of human malignancies. It is widely accepted that DNA is the cellular target for cisplatin. Prior to this work, several …
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