Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Tertiary Lymphoid Structures (TLS)"”.
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The role of B lymphocytes, plasma cells and tertiary lymphoid structures in the immune microenvironment of Non-Small Cell Lung Cancer
… και των τριτοταγών λεμφικών δομών (tertiary lymphoid structures, TLS). Οι TLS είναι έκτοποι λεμφικοί σχηματισμοί που αναπτύσσονται σε μη λεμφικούς ιστούς στο πλαίσιο χρόνιας φλεγμονής, συμπεριλαμβανομένου του καρκίνου, και προσομοιάζουν δομικά και λειτουργικά με τα δευτεροταγή …
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Mapping the spatial organisation of B cells and immune signalling in TNBC to characterise response to immunotherapy
In recent years, B cells and tertiary lymphoid structures (TLS) have emerged as key predictors of immunotherapy response across multiple cancers. B cells exist in various states of spatial organisation within the tumour microenvironment (TME), which likely support many of their functional roles. …
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Metabolic Disorders Rewire Systemic and Tumor Immunity to Shape Anti-Tumor Responses in Cancer Patients
… distort the architectural integrity of secondary lymphoid organs. This systemic decay disrupts germinal center organization and impairs the priming of effector cells, effectively collapsing coordinated humoral and cellular immunity before it even reaches the tumor. Locally, metabolic dysfunction …