Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Tendon injury"”.
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Preclinical translation of therapeutic interventions for tendon injury
The burden of injury to tendon and the attachment between tendon and bone (i.e., the tendon-bone attachment) on quality of life, disability, health care, and the economy is significant. Unfortunately, current therapeutic interventions have high re-injury rates and do not restore the optimized …
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Gene expression in healing tendon
Tendon injury is painful and often debilitating, and is a one of the most prevalent soft tissue injuries encountered in the clinic. While common, the underlying molecular and genetic processes of tendon damage and repair remain poorly understood. The work described herein used genome-wide …
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Equine superficial digital flexor tendon evaluation using low field magnetic resonance imaging and ultrasonography
… low field MR imaging for evaluation of equine tendon injuries over a 16 week period. The sample population was the superficial digital flexure tendon of eight young adult horses. The percentage of experimentally-induced tendon injury was evaluated in cross-section at the maximal area of injury …
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Whole exome sequencing: a customised approach to exploring the genetic basis of musculoskeletal soft tissue injuries
… 17) were previously associated with the risk of injury and were therefore prioritised for further interrogation. Variants within these regions, which had either been previously associated with injury risk or prioritised from the list of new candidates identified by whole exome sequencing (WES) …
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Determinants of positive functional outcomes at 16 weeks after flexor tendon repair at a teritiary hospital in South Africa. A descriptive, analytical study
… functional outcomes at 16 weeks after flexor tendon repair at a tertiary hospital in the Eastern Cape of South Africa: A descriptive, analytical study. Introduction: Flexor tendon injuries account for a substantial number of hand injuries presenting to health care facilities, yet …
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Once upon a sheep : a SEM analysis of ovine patellar enthesis
In tendon injury repair, the insertion of the tendon into the bone or enthesis often determines the quality of healing and poor enthesis often leads to treatment failure. However, natural enthesis is not very well understood and it is believed that the preparation methods of previous enthesis …
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Whole exome sequencing: a customised approach to exploring the genetic basis of musculoskeletal soft tissue injuries
… have previously been associated with the risk of injury and were therefore prioritised for further interrogation. Previously associated variants within these regions and/or new candidate variants identified by whole exome sequencing (WES) and prioritised through the application of a customised, …
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Development of 2D Ultrasound Tracking Software and Hardware to Monitor Multiple Flexor Tendon Displacement for Applications Toward Hand Prostheses
… to detect and track the displacement of flexor tendons within the human arm, using a non-invasive, ultrasound-based, speckle tracking technique. By tracking the tendons in the arm, it provides a way to monitor a person’s intention to move their hands and fingers. This has application to hand …
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A Comparison of the outcomes of two rehabilitation protocols after flexor tendon repair of the hand at Chris Hani Baragwanath Academic Hospital
Flexor tendon repair of the hand and rehabilitation are frequently discussed between hand surgeons and therapists. This is mainly due to the poor outcomes commonly achieved after this type of surgery. There are many patients in public hospitals in South Africa who require flexor tendon repair …
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Homing and Differentiation of Mesenchymal Stem Cells in 3D In Vitro Models
… mobilization and migration of endogenous MSCs to injury sites. MSC fate and function is determined by microenvironmental cues, specifically dimensionality, topography, and cell-cell interactions. MSC responses of migration and differentiation are the focus of this dissertation. Cell migration …
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Effects of Mechanical Damage on Patellar Tendon Ultrasound Texture Parameters
The patellar tendon assists in crucial daily motion of the knee such as knee extension. Partial tears or ruptures of this tendon have a prevalence of ~14% in elite athletes and 8.5% in nonelite athletes. Patellar tendon ruptures, caused by high demand tensile loading, often occur in tendons with …
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Anti-Inflammatory Effect of Adipose-Derived Mesenchymal Stem Cells for Flexor Tendon Healing
… surgical techniques over the past three decades, tendon repairs remain prone to poor clinical outcomes. While previous attempts to improve flexor tendon healing have focused on the later stages of healing: i.e., proliferation and matrix synthesis), the early inflammatory phase of tendon healing …
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Knotless bidirectional barbed versus smooth polypropylene three-loop pulley sutures for repair of canine gastrocnemius tendon
Canine common calcaneal (Achilles) tendon injury is a well-known cause of lameness in the dog. The Achilles tendon complex is primarily composed of the gastrocnemius tendon, with smaller contributions from the superficial digital flexor tendon and the common tendon of the biceps femoris, …
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Quantification of collagen fiber organization in biological tissues at cellular and molecular scales using second-harmonic generation imaging
… direction for three tissue types: porcine tendon, sclera, and ear cartilage. We find that both signal types yield consistent information on the preferred orientation of collagen fibers and several overlapping peaks in the magnitude spectrum for these tissues. This strengthens the …
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Comparison of bone marrow mesenchymal stem cells and tendon progenitor cells cultured on collagen surfaces
Tendon injuries are a significant cause of morbidity in performance horses with superficial digital flexor tendon injury reported to represent up to 43% of overall Thoroughbred racehorse injuries. Natural repair is slow and results in inferior structural organization and biomechanical properties …