Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 24 for “"Temporal Precision"”.
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EEG-Monitored Electrical Activity to Track Stored Information With High Temporal Precision
… (7.5-12.5 Hz). This study seeks to validate the temporal precision allowed with EEG by exploring the sensory systems responsible for governing visual working memory, specifically the manner in which populations of sensory neurons work together to create cognitive representations of relevant …
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Targeted read-out, analysis, and control to elucidate dynamic-emotional processing
… for pharmacological approaches that lack temporal precision. Here, a set of technologies and approaches for examining and treating these conditions are developed, using techniques to monitor brain activity and shut down specific brain sub-regions at times critical to the recall of …
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REMOTE CONTROL OF CELL FUNCTION USING TEMPERATURE AS AN INPUT
… from poor uptake, clearing, and a lack of spatio/temporal precision. Newer methods such as optogenetics suffer from the inability of light to penetrate tissue beyond a few millimeters. An attractive solution to overcome this challenge is using temperature as an inducer. Temperature can be …
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Advancing transport modelling for health applications
… travel. Existing methods are typically spatiotemporally aggregate and cannot offer insight into the mechanisms of behavioural change. Emerging methods from transport modelling could support health analyses by incorporating more advanced behavioural theory and capturing movements with high …
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Learning classification models of cognitive conditions from subtle behaviors in the digital Clock Drawing Test
… its position with considerable spatial and temporal precision, making available far more detailed data about the subject's performance. Using categorized stroke data from these drawings, we designed and computed a large collection of features, then explored the tradeoffs in performance and …
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Using Lidar to Examine Human Occupancy and Collisions within a Shared Indoor Environment
… throughout the semester with high spatial and temporal precision. Occupancy and collisions were highly related over several scales of temporal and spatial analysis. Furthermore, several interesting patterns emerged, including (a) collisions peaked early in the semester, then declined before …
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Quarkonium Suppression in pPb Collisions at CMS and Timing Detectors for Future Collider Experiment
… environments require simultaneous spatial and temporal precision. Beam tests demonstrate timing resolutions of 20–35 ps and spatial resolutions of 12–20 µm, establishing AC–LGADs as promising candidates for 4D tracking layers in future experiments, including the future Electron–Ion Collider.
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Developing a new CMBS hedging tool : a property price index-based synthetic
… depending on the investor's horizon or degree of temporal precision the investor seeks in the hedge, as well as the target tranche rating. The hedge ratio is very dynamic throughout the life of the synthetic, suggesting that the investor buying the synthetic for hedging purposes would need to …
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On the role of neuronal oscillations in auditory cortical processing
… appears to be a specialization of left A1 for temporal processing, as signified by greater temporal precision of neuronal oscillatory alignment. Taken together these results underline the importance of neuronal oscillations in perceptual processes, and the validity of the macaque monkey as a …
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Acute Manipulation of Erna Level For Dissecting Its Roles In Transcriptional Regulation
… systems to manipulate eRNA levels with high temporal precision. Three perturbation methods were tested on a testbed eRNA, including dCas9 based CRISPR activation or inhibition system and antisense oligonucleotide (ASO) based RNA inhibition system. I found that these CRISPR based systems show …
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Opto-fluidic neural probes for optogenetic brain interrogation
… signals with high sensitivity, spatial precision on the order of neurons, and temporal precision in milli seconds is the holy grail of neuroscience. To achieve this goal, novel tools to capture neurochemical dynamics with high spatiotemporal precision, and vast multiplexing ability are …
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Interferometric Scattering Microscopy: Theory, Simulation, and Experiment
… the nanoscale, and to what degree of spatial and temporal precision? My thesis seeks to develop the necessary theoretical and experimental framework to answer these questions through the lens of a specialized optical microscopy technique known as interferometric scattering (iSCAT), first …
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Individual differences in supra-threshold auditory perception - mechanisms and objective correlates
… subset of a very redundant set of spectral and temporal features. In stark contrast, communication in a complex, crowded scene places enormous demands on the auditory system. Spectrotemporal overlap between sounds reduces modulations in the signals at the ears and causes masking, with problems …
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4D mapping of network-specific pathological propagation in Alzheimer's disease
… in neither approach can achieve the spatial and temporal precision necessary to study the consequences of molecular insults across the brain over time. In this thesis, I capitalize on recent advances in tissue processing technologies to gain a network-level perspective on the molecular and …
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Dopaminergic Modulation Shapes Sensorimotor Processing in the Drosophila Mushroom Body
… neurotransmission with synaptic specificity and temporal precision to coordinately regulate the propagation of sensory signals through the output neurons. To explore how these output pathways ultimately influence olfactory navigation we have developed a closed loop olfactory paradigm in which we …
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Mechanisms of Olfactory Plasticity in Caenorhabditis Elegans
… to disrupt different parts of the circuit with temporal precision, I identified a group of neurons whose activity is required during adaptation. Finally, I performed functional calcium imaging of animals before and after adaptation, and determined that changes in neuronal responses to butanone …
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Deficits in inhibitory function mediate age-related multisensory and postural function decline
… adults. Specifically, reduced sensitivity to temporal delays between bimodal cues, can affect the reliability of perceptual representations and lead to difficulties discerning audiovisual speech. Poor motor and postural control are also a common consequence of natural aging which not only …
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Evaluation of Textile Force-Sensitive Resistors in Quantifying Athletic Shoe Fit
… tests, and the sensor outputs were evaluated on precision, accuracy, range, and temporal consistency. All four sensors demonstrated the expected inverse relationship between applied force and resistivity and had an adequate range and temporal precision for testing shoe fit. The results indicate …
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ms-Scale temporal coding in the thalamus predicted by whisker dispersive vibrational transduction
… a question of debate. Considering the remarkable temporal precision in the whisker system with spike timing as small as 10μs, there is potential for ultrahigh capacity information channel in kb/s. To study temporal structures in the stimuli that could be encoded by this information channel, highly …
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Neocortical Layer 4 to Layer 2/3 Sensory Information Processing Investigated with Digital-Light-Projection Neuronal Photostimulation
… of synaptic input from multiple synchronous or temporally correlated presynaptic locations. Here we describe a system that allows the generation of arbitrary 2-D stimulus patterns with thousands of independently controlled sites to manipulate the activity of populations of neurons with high …
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