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Showing 1 to 1 of 1 for “"Tcra Locus"”.

  1. The Role of Epigenetics in Regulating V(D)J Recombination and Allelic Exclusion

    … machinery. Moreover, once an antigen receptor locus has rearranged and produced a successful in-frame protein, a mechanism known as allelic exclusion prevents further recombination.</p><p>The nucleosome can positively and negatively regulate V(D)J recombination. Therefore, we defined the in …

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