Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Tc1"”.
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Low level Tc1 transposition and Tc1-induced mutations in dpy-5
The transposable element Tcl is the most thoroughly studied transposon in the nematode Caenorhabditiselegans. In this thesis I have examined Tcl transposition in the Bristol strain of C. elegans and analyzed Tcl-induced mutations in the dpy-5 gene of chromosome I. In the Bristol strain of C. …
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Degradation of atrazine utilizing triazine hydrolase (TrzN) from Arthrobacter aurescens TC1
… hydrolase (TrzN) from Arthrobacter aurescens TC1 is a Zn(II) dependent hydrolytic dehalogenase from the amidohydrolase super family. TrzN has 22 unique substrates. Most notably, TrzN can hydrolytically dechlorinate atrazine (2-chloro-4-ethylamino-6-isopropylamino-s-triazine) to its less toxic …
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Dissociated expression of granzyme B and IFN-gamma by T lymphocytes in HIV-1 infected individuals and its implications for Tc1 effector diversity
… correspond to Tc2 cells but represent a novel Tc1 subclass, which was termed Tc1c. Also the IFN-g positive, GzB negative CD8+ cell subpopulation represents a yet undefined CD8+ effector cell lineage that was termed Tc1b. Tc1b and Tc1c cells are likely to make different, possibly antagonistic …
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Effect of Process Parameters and Material Attributes on Crystallisation of Pharmaceutical Polymeric Systems in Injection Moulding Process. Thermal, rheological and morphological study of binary blends polyethylene oxide of three grades; 20K, 200K and 2M crystallised under various thermal and mechanical conditions using injection moulding
… 1 °C/min. Onset of crystallisation temperature (Tc1) was high for PEO2M and the difference between the 20K and 200K were pronounced at low cooling rate (20K is higher than 200K). The rheometer study showed that PEO2M has a solid-like structure around melting point which explains the difficulty in …
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Transcriptional and developmental consequences of aneuploidy during male meiosis
… we have used the trans-chromosomic mouse model, Tc1, which carries a single copy of human chromosome 21 (HsChr21) and show that, unlike other aneuploid mouse strains, the Tc1 mouse can successfully passage the exogenous human chromosome through male meiosis and generate aneuploid offspring. Our …
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DD34E DNA Transposable Elements of Mosquitoes: Whole-Genome Survey, Evolution, and Transposition
… analysis of DD34E TEs, which belong to the IS630-Tc1-mariner superfamily of DNA transposable elements, in the African malaria mosquito, Anopheles gambiae. Twenty-six new transposons as well as a new family, gambol, were identified. The gambol family shares the DD34E catalytic motif with Tc1-DD34E …
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Immunogenetic regulation of Natural Killer cell function in pregnancy
… NKR genes in isolation, I used congenic B6.BALB-TC1 (TC1) mice that differ from C57BL/6 (B6) mice only within the region of chromosome six encoding NKRs that recognise MHC class I. Absence of a major inhibitory NKR for self-MHC, Ly49I, in TC1 mice causes a compensatory shift in the NKR repertoire …
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RUOLO DEL RECETTORE GABAA NELLE CELLULE ALFA PANCREATICHE E SUO COINVOLGIMENTO NELLE FASI DI DESENSIBILIZZAZIONE INDOTTA DALLA LIPOTOSSICITA NEL DIABETE DI TIPO II.
… di alfa cellule pancreatiche. Le cellule alfa-TC1-C6 sono state coltivate in presenza o in assenza di palmitato (0,5 mmol / l) per 48 h. Al termine del trattamento si osservava un aumento della secrezione basale di glucagone, induzione di uno stato di insulino-resistenza (diminuzione della …
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A Framework for Object Recognition in Construction Using Building Information Modeling and High Frame Rate 3D Imaging
… Reference Resource schemas within the IFC 2x3 TC1 architecture. Within this framework a new Property Set (Pset_ObjectRecognition) is suggested which provides an on-demand capability to access available feature descriptor information either embedded in the IFC model or referenced in an external …
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Can levamisole upregulate the equine cell mediated immune response in vitro?
… dendritic cell (DC1) CD4 T-helper 1 (Th1) CD8 Tc1 immune response in vitro. The first aim was to determine optimal conditions and effects of levamisole on cellular proliferation. Equine PBMCs were harvested from ten horses seronegative for S. neurona. The cells were cultured alone, or with one …
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Molecular mechanisms of T cell homing in Hodgkin's lymphoma : implications for T-cell-based therapies
… T cell therapy were found to express a polarised Tc1 phenotype (CXCR3, CXCR6 and ccr5), which was typically independent of target antigen specificity, CD4/CD8 and donor status. However, lack of CCR7 expression and an inability to capture to VCAM-1 in a chemokine dependent manner suggested that …
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A Mosquito DNA Transposon Agh1: Structure, Evolution and Evidence of Activity
… most DD34E transposons that are similar to the Tc1 family, AGH1 belongs to a different clade that is related to the previously characterized fungal TE Ant and protozoan TEC1 and TEC2. Truncated AGH1 and AGH1-related MITE (Miniature inverted-repeat TE) families were also identified. AGH1 …
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Molecular Analysis of <i>Trypanosoma cruzi</i> Isolates Obtained from Raccoons (<i>Procyon lotor</i>) in Warren and Barren Counties of Kentucky
… spacer of the mini-exon genes (TC, TC1, and TC2), the 18S rDNA sequence (V1 and V2), and TCZ1 and TCZ2 primers that amplify a 188-base pair segment of the repetitive 195-bp nuclear DNA sequence of <i>T. cruzi</i>. DNA sequencing (ABI 3130 Genetic Analyzer) was performed on all …
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A genetic and molecular analysis of the bli-4 locus of Caenorhabditis elegans, an essential gene encoding KEX2-like subtilisin-typw serine endoproteases
… an insertion of the 1.6 kb transposable element, Tc1.Three protein products that differ at the carboxyl end, are predicted from alternately spliced bli-4 cDNA clones. The predicted proteins were designated blisterin A, blisterin B and blisterin C according to the order that the variantly spliced …
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Transcription factor modulation in T-cells to improve cancer immunotherapy
… robustly and produced elevated levels of TH1/TC1-associated cytokines upon in vitro restimulation with tumor. AhRi CAR-T further mediated superior tumor control in mice bearing human lymphoma xenografts. Our data expand the mechanisms by which NOTCH can shape CD4+ T-cell behavior, and …
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Interactive Association Between Molecular Structure Spectral Profiles and Nutrient Utilization and Availability of Leaf, Stem, Pods, and Whole Plant Faba Bean Forage in Ruminants Before and After Rumen Incubation
… parameters of total carbohydrate first peak (TC1) height and cellulosic compounds (CEC) peak height and peak area, spectral intensity was increased after incubated in the rumen. Faba bean samples significantly interacted with incubation time for other spectral profiles. With multivariate …