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Showing 1 to 1 of 1 for “"Tau seeding"”.

  1. An investigation into the role of LUBAC and linear ubiquitin chains in antibody dependent intracellular neutralisation

    … during antibody- mediated protection against tau seeding. This is a novel use of ADIN and shows promise in immunotherapy against Alzheimer’s disease. I found that siRNA technology was not suitable for this assay. Overall, I have demonstrated that HOIP and linear ubiquitin chains promote …

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