Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Taste masking"”.
-
Insights of Taste Masking from Molecular Interactions and Microstructures of Microspheres
The effects of taste masking are determined by interactions between drug and excipients as well as the microstructures of the particulate drug delivery systems (DDS). Cyclodextrin (CD) is a widely used taste masking agent, to which the relationship between kinetic parameters (Ka and Kd) of a drug …
-
Solubility enhancement, mechanical properties and taste masking of poorly water soluble compounds by optimizing hot melt extrusion processing
… including solid-state stability enhancement, taste masking, and solubility enhancement, and can be used in the production of a variety of drug dosage forms. The use of HME for solubility enhancement is the subject of this research. Solubility enhancement can be achieved by using HME to …
-
Versatility of hot-melt extrusion for dosage form design
… different goals, such as solubility enhancement, taste masking, solid state stability enhancement, and sustained release formulations for oral drug delivery, using one model drug, mefenamic acid. For solubility enhancement and taste masking formulations, Eudragit EPO was blended with MA in …
-
Patient Friendly Formulations Utilizing Hot Melt Extrusion Technology
… using e-tongue, to assess the extent of masking of bitter taste of the API. There was an insignificant amount of drug released from the formulation in the salivary medium while over 80% of drug released within 30 min in 0.1 N HCl. ODTs were also developed with the extrudate mixed with …
-
USE OF HYPROMELLOSE AND HYDROXYPROPYL CELLULOSE TO DEVELOP AN AGE APPROPRIATE PLATFORM TECHNOLOGY FOR THE ADMINISTRATION OF MEDICINES TO CHILDREN
… flexibility, dose accuracy, afford acceptable taste of undesirable tasting drug substances and be suitable for administration to all paediatric sub groups. To ensure affordability and thus enhance access to medicines for children in developing countries or emerging markets, the dosage form …
-
Characterization of different hydrophilic polymers and their applicability in hot melt extrusion technology
… process. Some of the HME applications include taste masking, solid-state stability enhancement, solubility enhancement etc. Solubility enhancement in the HME process occurs through the dispersion of a poorly soluble drug in a polymeric carrier matrix essentially forming a solid dispersion. …
-
Development of hot-melt extrusion as a novel technique for the formulation of oral solid dosage forms
… The in vitro and in vivo evaluation of the masking efficiency of hot melt extruded paracetamol (PMOL) formulations was examined. Extruded granules containing high PMOL loadings in Eudragit EPO® (EPO) or Kollidon® VA64 (VA64) were prepared by HME. Similarly propranolol HCl (PRP), …