Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 7912 for “"Targeted"”.
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Targeted persuasive advertising
… it. The second essay considers the use of targeted advertising in duopoly, when one of the firms does not have access to advertising. I find that advertising will target those consumers most likely to switch to the non-advertising firm. Each firm sets a price just high enough to capture the …
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EGFR-Targeted Polymeric Micelles For Targeted Pc 4-PDT Of Oropharyngeal Tumors
… develop an effective nanomedicine platform for targeted delivery of the photosensitizer drug Pc 4 to sites of head and neck cancer to enhance the clinical repertoire of Pc 4-induced photodynamic therapy (PDT) in these malignancies. The specific aims are to: (1) Determine encapsulation and …
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Integrin-targeted cancer immunotherapy
Integrins are a family of heterodimeric cell surface receptors that are functionally important for cell adhesion, migration and proliferation. Certain integrins, especially those that are known to recognize the arginine-glycine-aspartate (RGD) motif, are heavily overexpressed in many cancers …
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Magnetic Targeted Drug Delivery
Methods of guiding magnetic particles in a controlled fashion through the arterial system in vivo using external magnetic fields are explored. Included are discussions of applications, magnetic field properties needed to allow guiding based on particle characteristics, hemodynamic forces, the …
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Targeted delivery of biological agents
… needed for the generation of a successfully targeted Ad35 vector. This helps understanding of the requirements for a successful treatment for cardiovascular disease and cancer.
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Targeted killing of suspected terrorists
Targeted killing by drones has become a common tool of lethal force in the "war on terrorism" in the past decade. Owing to the specific nature of targeted killing by drones and suspected terrorists, this method of warfare does not easily fall under one particular model of international law. The …
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Targeted drug delivery within the eye
… in a rabbit model. The data show that highly targeted delivery of the anti-vascular endothelial growth factor protein therapeutic gave a better biological response of suppressing neovascularization with 11,900 times less dosage compared to topical administration. The second part of the …
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Targeted magnetic hyperthermia for lung cancer
… change and induce resistance. Additionally, non-targeted delivery of these particles to the healthy tissues can result in toxicity. To overcome these problems, we used aerosol-based, tumor-targeted SPIO nanoparticles to induce highly selective hyperthermia for the treatment of lung …
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Targeted therapies in mantle cell lymphoma
… Rituximab is a chimeric monoclonal antibody targeted against B cells and both Rituximab-sensitive and insensitive MCL models were defined. An abnormally high expression of bcl-2, bcl-x L, mcl-1, CD40/CD40L and Fas were observed in all MCL cells, as well as high levels of soluble FasL, capable …
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Analysis of AUF1 targeted mRNA sequences
AUF 1, an A+U rich element (ARE) binding protein, plays an important role in mRNA decay. To identify the mRNAs that interact with AUF 1, mRNA derived from a human cardiac cDNA expression library was purified by AUF 1 affinity chromatography and cloned following RT-PCR. 261 sequences were obtained. …
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Dynamic Targeted Pricing in B2B Settings
… an integrated framework for inter-temporal targeted pricing to optimize long-term profitability for the firm. Pricing decisions in B2B settings are inherently different from those within the business-to-consumer (B2C) environment, commonly studied in marketing. First, B2B pricing often …
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Secondary anchor targeted cell release system
The lack of diagnostic tools that can probe individual heterogeneities in patient’s cell receptor expression limits advancement in personalized medicine. These individual differences in receptor quantities can give rise to both intrinsic and acquired resistances to therapeutics, which result in …
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Location-targeted measurement of perceived stress
Modern medicine has made significant advancements in the treatment of acute diseases, disorders, and injury. However, the acute care system rising from the twentieth century medical industry is far less adept in tracking and managing the needs of chronic conditions, especially that of chronic …
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Targeted Sanctions and Sovereignty in Zimbabwe
The emergence of targeted sanctions marked a moment of global optimism, wherein leaders who defied ‘acceptable’ international norms and other transgressors could face consequences, while at the same time shielding vulnerable populations from these consequences. This novel approach to sanctions …
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Targeted Priority Mechanisms in Organ Transplantation
… This dissertation develops and analyzes targeted priority mechanisms, voluntary incentive-based programs designed to enhance access for disadvantaged patient groups and improve organ-recipient matching. Using a rigorous queueing-theoretic framework, I characterize patients' equilibrium …
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Distributive considerations of a targeted price control
We review the literature on price controls and build a model that analyses shot-term dis- tortions on relative prices of product categories that are either directly or indirectly affected by price controls. According to the model, their imposition on low-end basic necessities might seem a …
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ESIMS targeted synthesis of novel {Pt2S2} derivatives
Electrospray ionisation mass spectrometry (ESIMS) was used to investigate ring- opening reactions of several epoxides with the nucleophilic dinuclear PtII complexes [Pt2(μ-E)2(PPh3)4] (E = S, 1a; Se, 1b) and several activated cyclopropanes, N - tosylaziridine, and thiirane with 1a. Epoxides …
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