Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"Target prioritisation"”.
-
"Sugar Coat" Genetic & chemical validation of <i>Aspergillus fumigatus</i> cell wall targets
… what is required is the characterisation of new targets possessing novel modes of action. The work presented in this thesis addresses this evolving area of unmet clinical need using a target-based approach to assess a miniature portfolio of enzymes that are involved in the synthesis and …
-
OPTIMISATION AND THERAPEUTIC-TARGET-DISCOVERY ORIENTED ANALYSIS OF CRISPR-CAS9 SCREENS
… has revolutionized cancer research by enabling targeted genome modifications in tumour cells, offering insights into cancer biology and potential treatment targets. My PhD research focuses on developing tailored tools and pipelines to enhance the analysis of CRISPR-Cas9 screens for identifying …