Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Target delivery"”.
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ENGINEERING MAGNETIC DEVICE AND NANOPARTICLES PLATFORMS TO IMPROVE DRUG ACCUMULATION AND PENETRATION IN TUMORS FOR ENHANCED CANCER TREATMENT
Drug delivery strategies aim to maximize the accumulation of therapeutic agents at targeted sites, such as tumors, while minimizing off-target delivery to healthy tissues, thereby enhancing therapeutic efficacy and reducing unwanted side effects. Nanoparticles have garnered significant interest as …
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The conjugation and evaluation of hydrophobic small molecules to trazole-linked siRNAs
… which gives rise to their high degree of mRNA target specificity and their catalytic nature. However, the full potential of these therapeutic drugs will not be attained unless better methodologies are developed to enhance target delivery and to enhance resistance to ribonuclease-mediated …
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Exploring Critical Vehicle Parameters for the Design of Multitargeted Nanoparticles for Cancer Specific Gene Delivery
… of cancer gene therapy is lack of effective delivery tools. Gene delivery vehicles must protect against degradation, avoid immunogenic effects and prevent off target delivery which can cause harmful side effects. The stealth liposomes has greatly improved tumor localization of small molecule …
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Drug Loaded Multifunctional Microparticles for Anti-VEGF Therapy of Exudative Age-related Macular Degeneration
… of therapies. We propose to develop a drug delivery system that could perform sustained release of anti-VEGF drug by multifunctional drug-loaded microparticles (MPs).</p><p>A modified double emulsion technique has firstly been used to fabricate biodegradable poly-lactic-co-glycolic acid …
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Cell squeezing : a vector-free microfluidic platform for intracellular delivery of macromolecules
Intracellular delivery of material is a long-standing challenge for both therapeutic and research applications. Existing technologies rely on a variety of mechanisms to facilitate delivery. Vector-based methods, such as polymeric nanoparticles and liposomes, form complexes with the target material …