Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"Tanaproget"”.
-
Computational and synthetic approaches in the design and development of chemical probes for estrogen receptor function
… docked structures of fluorinated analogues of Tanaproget for the progesterone receptor (PR), whose expression is tightly controlled by ER. These functions have been applied in the design and selection of new synthetic targets for use in imaging ER-positive tumors via positron emission …
-
Evaluation of new PET tracers for receptor tumour imaging
… PR ligands was synthesized based on the Tanaproget pharmacophore. The lead radiotracer, 18F-fluoropyridine was further assessed by in vitro and in vivo assays. 18F-Fluoropyridine in vitro uptake was showed to be receptor-mediated, however the in vivo imaging in hormone treated mice showed …