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Showing 1 to 3 of 3 for “"Tamoxifen Sensitivity"”.
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Expression And Regulation Of Map Kinase Phosphatases 1 And 2 In Breast Cancer Tamoxifen Sensitivity
… MAP KINASE PHOSPHATASES 1 and 2 IN BREAST CANCER TAMOXIFEN SENSITIVITY</strong> </p> <p>by</p> <p> <strong>KELLY K. HAAGENSON</strong> </p> <p> <strong>May 2013</strong> </p> <p> <strong>Advisor:</strong> Dr. Malathy Shekhar</p> <p> <strong>Co-Advisor:</strong> Dr. Gen Sheng Wu</p> <p> …
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Cell cycle regulatory proteins and miRNAs in premalignant lesions and breast cancer
… p27 was associated with impaired response to tamoxifen in premenopausal breast cancer patients, but not with prognosis. We have also observed that the expression of the microRNA (miRNA) miR-92a could provide independent prognostic information in breast cancer patients, and loss of miR-92a was …
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Mechanism of tamoxifen resistance in breast cancer
<p>Acquired tamoxifen resistance develops in the majority of hormone responsive breast cancers and frequently involves overexpression of the PI3K/AKT axis. Here, breast cancer cells, with elevated endogenous AKT or overexpression of activated AKT exhibited tamoxifen-stimulated cell proliferation …