Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Tail-anchored proteins"”.
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Investigations Into the Function of Elp3 in Toxoplasma Gondii
… survey that discovered over 50 additional “tail-anchored” proteins present in Toxoplasma. Mutational analyses found that targeting of these TA proteins to specific parasite organelles was strongly influenced by the TMD sequence, including charge of the flanking C-terminal sequence.
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Regulation of the Target of Rapamycin Signaling Pathway in Saccharomyces cerevisiae
… protein localization of fluorescence tagged proteins was employed to determine the function of an essential protein, Lst8, in TORC1 and TORC2 signaling and a previously uncharacterized complex, the Far3-7-8-9-10-11 complex (Far complex) in the budding yeast, <em>Saccharomyces cerevisiae</em>. …
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Structure and Function of the ER-Membrane Complex
… and the biogenesis of multi-pass membrane proteins. Although the complex was formally identified nearly 10 years ago, direct biochemical evidence for functional roles is sparse. Only in the last two years have mechanistic roles been characterised in the insertion of tail-anchored proteins …
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Membrane protein biosynthesis at the endoplasmic reticulum
The biosynthesis of integral membrane proteins (IMPs) is an essential cellular process. IMPs comprise roughly 20-30% of the protein coding genes of all organisms, nearly all of which are inserted and assembled at the endoplasmic reticulum (ER). The defining structural feature of IMPs is one or more …
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Distinct C-terminal Amino Acid Sequence Motifs Serve as the Targeting Signals for Outer Mitochondrial Membrane and Plastid Outer Envelope TA Proteins
Tail-anchored (TA) proteins are a unique class of functionally diverse membrane proteins that are defined by their single C-terminal transmembrane domain and their ability to insert post-translationally into specific organelles in an Ncytosol-CIMS orientation. While in recent years considerable …