Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Tablet formulation"”.
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Designing A Calibration Set in Spectral Space for Efficient Development of An NIR Method For Tablet Analysis
… for quantitative analysis of pharmaceutical tablets. This step is critical because successful model development depends on the suitability of the calibration data. For spectroscopic-based methods, traditional concentration based techniques for designing calibration sets are prone to have …
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An Assessment Of Forcite Approaches In Predictiing Young’s Modulus From Crystal Structure
Improving the efficiency of tablet manufacturing in pharmaceutical industry has always attracted great concern. The mechanical properties of drugs are important for successful tablet production Thus, the knowledge of mechanical properties of pharmaceutical compound in pre-formulation stage …
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Knowledge refinement for a formulation system.
… KRUST to the design system TFS, whose task is tablet formulation for a major pharmaceutical company. KRUST has already been successfully applied to a variety of classificatory problems, and a generic refinement framework is being developed. This thesis explores the differences in knowledge …
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Lipid & surfactant based systems for improved delivery of poorly soluble APIs
… been utilized in improving the handling, ease of formulation, solubility and bioavailability of three compounds. In the first study, studies have been performed to formulate Δ9-THC into a sustained release tablet, using lipid matrices, for the treatment of chemotherapy induced nausea and vomiting …
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A pharmacometric approach to optimal use of second line drugs for multidrug-resistant tuberculosis
… compare the exposures of crushed versus whole formulations of pyrazinamide, moxifloxacin, ethionamide, ethambutol, cycloserine, and isoniazid. Results and conclusions We found no measurable terizidone in plasma supporting the hypothesis that terizidone is hydrolysed pre-systemically to …
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Development of paediatric dosage forms of furosemide using the problem structuring method of morphological analysis
… counteract this deficiency bespoke, unlicensed formulations are formulated by contract manufacturers, hospitals and dispensing pharmacists using a variety of ‘recipes’ and differing manufacturing protocols. In this work, Morphological Analysis as a problem structuring method is deployed using …
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Tabletability Flip of Drugs upon Formulation
Tabletability is a key property that determines a powder’s ability to form tablets under applied stresses, typically represented by a plot of tablet tensile strength versus pressure. Tablet tensile strength reflects the contributions of interparticulate bonding area (BA) and bonding strength (BS) …
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Oral Drug Delivery -- Molecular Design and Transport Modeling
… model can also be used to design the drug tablet for target pharmacokinetic characteristics. The advantage of the suggested approach is that it includes the mechanism of drug release and also the properties of the polymer carrier into the model. The model is flexible and can be adapted …