Global ETD Search
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Showing 1 to 5 of 5 for “"Tablet compaction"”.
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Pharmaceutical tablet compaction : product and process design
This thesis explores how tablet performance is affected by microstructure, and how microstructure can be controlled by selection of excipients and compaction parameters. A systematic strategy for formulation and process design of pharmaceutical tablets is proposed. A modified nanoindenter method …
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Microstructural investigation of tablet compaction and tablet pharmacological properties
In current tablet manufacturing processes, there is a knowledge gap concerning material transformation and the subsequent impact on tablet properties; this gap presents a barrier to rational formulation / process design. In this study, it was hypothesized that the understanding of tablet …
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A STUDY OF COMPRESSION DIE DESIGN ON THE COMPACTION OF PHARMACEUTICAL POWDER
Tablet quality can be affected by feed material, process parameters, equipment configuration and tooling design. Tableting die is part of the compaction tooling and determines tablet size and shape. Dies with modified designs could potentially address tablet compaction issues, such as low tensile …
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Role of Mechanical Stress, Excipients and Coprocessing On Tablet Mechanical Properties
… of compression speed and powder co-processing on tablet mechanical properties. In the first chapter, the effect of compression speed on compressibility, tabletability, and compactibility profiles of various materials was explored. The advantage of utilizing a compactibility profile in reducing the …
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Modeling picking on pharmaceutical tablets
<p>Tablets are the most popular solid dosage form in the pharmaceutical industry because they are cheap to manufacture, chemically and mechanically stable and easy to transport and fairly easy to control dosage. Pharmaceutical tableting operations have been around for decades however the process is …