Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"TSPO"”.
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Development of PET Radiotracers for Imaging Neurodegeneration: Targeting alpha-Synuclein Fibrils and TSPO
… the 18 kDa mitochondrial translocator protein (TSPO). This work has involved the synthesis and characterisation of novel compounds that have the potential for being applied as radiotracers for imaging α-synuclein fibrils (project 1), or TSPO (project 2) via PET. Over the course of project 1 a …
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Characterization of TSPO expression and radioligand-binding in the central nervous system and peripheral blood in neuroinflammatory disease
… young adults. The 18 kDa Translocator Protein (TSPO) is a mitochondrial protein and positron emission tomography (PET)-imaging target that is highly upregulated in MS brain lesions and may potentially represent both an inflammatory biomarker and a therapeutic target for the monitoring and …
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The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
… involved in steroidogenesis; namely Lhcgr, Star, Tspo, Cyp11a1, Cyp17a1 and Hsd17b3, as well as for Gapdh as a housekeeping gene. TM4 cells were also assayed for inhibin B secretion, lactate secretion and SCB integrity (by transepithelial electrical resistance). Within the tested concentration …
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Mobile genetic elements as modulators of the human gut symbiont Bacteroides
… repression of a tryptophan-rich sensory protein (TspO), and represses bile acid deconjugation. Because microbially-modified bile acids are important signals for the mammalian host, this represents a mechanism by which a phage may influence mammalian phenotypes. Furthermore, BV01 and its relatives …
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ENZYMOLOGY AND MOLECULAR BIOLOGY OF BILE ACID 7alpha- AND 7beta- DEHYDROXYLATION BY THE INTESTINAL BACTERIA CLOSTRIDIUM SCINDENS AND CLOSTRIDIUM HYLEMONAE
… similar to the Tryptophan-rich sensory protein (TspO)/mitochondrial peripheral benzodiazepinereceptor (MBR) family of proteins.