Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"TRN"”.
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Single-cell transcriptomics of the mouse thalamic reticular nucleus
The thalamic reticular nucleus (TRN) is strategically located at the interface between the cortex and the thalamus, and plays a key role in regulating thalamo-cortical interactions. Current understanding of TRN neurobiology has been limited due to the lack of a comprehensive survey of TRN …
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Causal control of the thalamic reticular nucleus using optogenetic and novel chemogenetic approaches
… the gate may be the thalamic reticular nucleus (TRN). The TRN is a primary source of GABAergic input to thalamic relay nuclei. The TRN projects directly to the rest of thalamus, generating feedforward and feedback inhibition. It is therefore positioned to mediate forebrain function, and …
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Investigating the regulation and evolution of tartan during Drosophila male genital diversification
… mauritiana have identified that the gene tartan (trn) is involved in the evolution of the surstyli (claspers) which form part of the external male genitalia. trn encodes a leucine-rich repeat transmembrane protein and contributes to the difference in surstyli size and the bristle number between D. …
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PERFORMANCE OF A ROBUST MULTIPLE-RING, MULTIPLE-TOKEN NETWORK
… studies of multiple-ring Token Ring Networks (TRNs) in which all nodes are connected to all rings [4,5] show that the packet transfer delay improves with the number of rings connected to each node. However, such multiple-ring TRNs are not economically feasible as the cost of the ring interface …
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Microtubules, Acetylation, and MEC-3 Regulated Genes in C. Elegans Mechanosensations
… is mediated by the six Touch Receptor Neurons (TRNs). TRN cell fate is specified by the LIM-Homeodomain transcription factor MEC-3. Gene expression profiling has revealed a set of putatively MEC-3 dependant transcripts, which may represent the set of genes necessary to establish a TRN fate. I …
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Visual Terrain Relative Navigation: Pose Estimation, Neural Fields, and Verification
Visual Terrain Relative Navigation (TRN) is a method for GPS-denied absolute pose estimation using a prior terrain map and onboard camera. TRN is commonly desired for applications such as planetary landings, unmanned aerial vehicles (UAVs), and airdrops, where GPS is either unavailable or cannot be …
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Cellular and Circuit Properties of Slow Oscillations In The Thalamic Reticular Nucleus
… neurons in the thalamic reticular nucleus (TRN) generate distinct types of oscillatory activity. While the reciprocal synaptic circuits between TRN and sensory thalamic nuclei underlie the generation of sleep spindles, the mechanisms regulating slow (<1 >Hz) forms of thalamic oscillations …
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Auditory Processing Deficits in MSH2-KO mice are linked to Aberrant Inhibitory Neuron Function in the Thalamic Reticular Nucleus
… we focused on the thalamic reticular nucleus (TRN): a critical regulator of corticothalamic and thalamocortical activity. We observed an increase in parvalbumin (PV<sup>+</sup>) expression, density, and cell area in the TRN, as well as high aggregation of the gap junction protein connexin-36 …
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Investigating the functional effects of genes involved in genital divergence between Drosophila species
… D. mauritiana. To date, only two genes, tartan (trn) and sox21b, have been identified as contributing to size differences in male genital structures, with trn influencing clasper size divergence and sox21b contributing to divergence in posterior lobe size between D. simulans and D. mauritiana. …
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The genetic and developmental bases of male genital organ size evolution
… reciprocal hemizygosity test showed that tartan (trn), underlies clasper size evolution between these species. Trn is a Leucine Rich Repeat transmembrane protein, and is the first gene identified underlying genital organ size differences between species. Moreover, expression analysis of trn …
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Structure and topology of transcriptional regulatory networks and their applications in bio-inspired networking
… adversities. Transcriptional Regulatory Network (TRN) is one such biological network that is formed due to the interaction between proteins, called Transcription Factors (TFs), and segments of DNA, called genes. TRNs are known to exhibit functional robustness in the face of perturbation or …
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Outlier-Robust Multi-View Triangulation Using Graduated Non-Convexity for Space Vehicle Navigation
… is used in terrain relative navigation (TRN) to identify the position of terrain features with respect to the spacecraft and to ultimately estimate the spacecraft’s pose during planetary landing and navigation. This thesis seeks to improve current multi-view triangulation methods to …
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Regulation of Thalamic Neuron Excitability and Intrathalamic Rhythms by Vasoactive Intestinal Peptide
… properties of thalamic neurons in dorsal TRN, putative visual TRN. My results suggest that VIP-related peptides depolarize thalamic relay neurons and these actions clearly influence intrathalamic rhythmic activities. These peptides may play a significant role in regulating information …
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Publication and Registration Bias in Randomized Clinical Trials
… the reporting of the trial registration number (TRN), and the publication rates of digital health RCTs registered in any of the World Health Organization (WHO) registries. To improve the external validity beyond the realm of digital health RCTs, the third study provided an empirical analysis of …
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Neuromodulation of Inhibitory Activity in Thalamocortical Circuits
… currents arising from interneurons and TRN neurons can be distinguished by their kinetics. The local interneurons are of interest because these neurons have two distinct outputs: axonal and dendritic. These cells have classical axonal outputs, termed F1 terminals, as well as presynaptic …
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Phylogeography and population genetics of two forest endemic mosses in the Cape Floristic Region
… valentiniana. Two gene regions were used, trnLF (chloroplast genome) and ITS1 (nuclear genome). Neckera valentiniana showed no variation from the populations sampled. Results from Leptodon smithii based on the trn and ITS region suggest that forests once were widespread, but then became …
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Phylogeny of the Genus Arachis and its Application to the Evolution of the Major Peanut Allergen Ara h 2
… based on sequence information from plastid <i>trn</i>T-<i>trn</i>F and nuclear ITS genomic regions. Phylogenetic analysis resolved section <i>Extranervosae</i> at the base, followed by sections <i>Triseminatae</i> and <i>Caulorrhizae</i>. Two major terminal lineages were recovered. One is …
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Molecular analysis of genes involved in carbohydrate metabolism in the desiccation-tolerant cyanobacterium Nostoc commune UTEX 584
… Further upstream of the promoter lies <i>trn</i>K encoding lysyl-tRNA, identified by evident similarity to the corresponding gene from the chloroplast of the liverwort, <i>Marchantia polymorpha</i>. The remainder of the aldolase gene (<i>fba</i>) was isolated using the colony hybridization …
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The Cellular and Molecular Dynamics of the Queuosine Modification in Transfer RNA: Definition, Modulation, Deficiencies and Effect of the Queuosine Modification System
… queuosine modification in the wobble position of tRNA<sup>asn</sup>, tRN<sup>asp</sup>, tRNA<sup>his</sup>, and tRNA<sup>tyr</sup> is associated with a decrease in cellular growth rate, an increase in the ability to withstand environmental stress, and differentiation of pleuripotent cells into …
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DNA Repair Deficiency in Huntington's Disease Fibroblasts and Induced Pluripotent Stem Cells
… thus providing a possible mechanism for TRN instability. Using quantitative polymerase chain reaction (qPCR) gene arrays for 84 DNA repair genes, we identified 18 DNA repair genes with decreased fold changes between 2- and 3- fold, as well as 11 genes down regulated greater than 3- fold …
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