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Showing 1 to 1 of 1 for “"TRMT5"”.
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Characterisation of RNA modifications in human cancer cells
… is present on mRNA where it is catalysed by TRMT5, an enzyme previously identified as a tRNA methyltransferase (TRMT). Utilising ribosome profiling, I found that loss of TRMT5 greatly affects global protein translation. Moreover, depletion of TRMT5 from the PDAC cell line, PANC-1, inhibited …