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Showing 1 to 2 of 2 for “"TRIM22/Staf50"”.
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TRIM22/Staf50 - a novel target gene of the tumor suppressor p53
… Using a cDNA microarray analysis, I identified TRIM22/Staf50 as a novel direct target gene to p53. The function of TRIM22 is largely unknown apart from being an interferon inducible protein and its involvement in inhibiting virus infection. TRIM22 belongs to the family of TRIM proteins (RBCC …
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On the function of the interferon-inducible p53 target gene TRIM22
The interferon-inducible p53-target gene TRIM22 (Staf50) is a member of the TRIM (TRIpartite Motif) family. The TRIM family is a family of RING (Really Interesting New Gene) proteins, defined through a tripartite motif, containing a RING-domain, one or two B-boxes and a Coiled-coil-domain. The TRIM …