Global ETD Search
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Showing 1 to 4 of 4 for “"TRIM22"”.
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On the function of the interferon-inducible p53 target gene TRIM22
The interferon-inducible p53-target gene TRIM22 (Staf50) is a member of the TRIM (TRIpartite Motif) family. The TRIM family is a family of RING (Really Interesting New Gene) proteins, defined through a tripartite motif, containing a RING-domain, one or two B-boxes and a Coiled-coil-domain. The TRIM …
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TRIM22/Staf50 - a novel target gene of the tumor suppressor p53
… Using a cDNA microarray analysis, I identified TRIM22/Staf50 as a novel direct target gene to p53. The function of TRIM22 is largely unknown apart from being an interferon inducible protein and its involvement in inhibiting virus infection. TRIM22 belongs to the family of TRIM proteins (RBCC …
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Analysen zu TRIM-Genen in Primaten
… während innerhalb des 11p15-Clusters TRIM21 und TRIM22 neben TRIM5a Anzeichen von positiver Selekion aufweisen. Insbesondere bei getrennten Analysen von Tripartite Motif und B30.2-Domäne konnte festgestellt werden, dass bei TRIM21 das Tripartite Motif leichte Anzeichen einer positiven Selektion …
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Using machine learning to increase the predictive value of humanized mouse models for the human immune response to YFV-17D
… immune response, and interferon signaling. TRIM22 and TRIM5, and potentially related genes, may be reliably uncovered by semi-supervised ML models applied to humanized mouse models, though further study is required for verification. Overall, modified humanized models, combined with ML …