Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"TRIB2"”.
-
An investigation of the role of TRIB2 in steady state and stressed haematopoiesis
TRIB2 is a member of the mammalian Tribbles family of serine/threonine pseudokinases (TRIB1-3). Here, we studied murine haematopoiesis after Trib2 ablation under steady state and proliferative stress conditions, including genotoxic and oncogenic stress. At the steady state, we found that TRIB2 loss …
-
The Roles of the Drosophila Protein Tribbles in Oogenesis and Insulin Signaling Pathway
… signaling. In recent years, mammalian Trib3 and Trib2 proteins have been implicated in the regulation of Insulin signaling by inhibiting the activating phosphorylation of Akt, Given the central role of Akt in insulin signaling, I tested whether the function of Trib family in insulin signaling is …